Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol:	Whrnwi
Name:	whirlin; whirler
MGI ID:	MGI:1857090
Synonyms:	wi
Gene:	Whrn  Location: Chr4:63333147-63414228 bp, - strand  Genetic Position: Chr4, 33.97 cM, cytoband C1
Alliance:	Whrnwi page

Strain of Origin:

STOCK a Tyrp1b Myo5ad Oca2p Ednrbs

Allele Type:    Spontaneous Mutation:    Intragenic deletion   Mutation details: The mutation was identified as a 526 bp deletion encompassing the first putative methionine of the short C-terminal isoform and part of the long isoform. This creates a frameshift resulting in premature termination of the long isoform before the third PDZ domain. This deletion encompasses the majority of exons 6-10 of the gene, thus resulting in the ablation of both the long (WHRN-L) and the short (WHRN-S) isoforms. (J:86904, J:235390) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

10 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available      Cell Lines: 0 lines available
Carrying any Whrn Mutation:	46 strains or lines available

Original:	J:269 Lane PW, Whirler mice, a recessive behavior mutation in linkage group VIII. J Hered. 1963 Nov-Dec;54:263-6
All:	30 reference(s)