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Nudt5 Gene Detail
Summary
  • Symbol
    Nudt5
  • Name
    nudix hydrolase 5
  • Synonyms
    nudix (nucleoside diphosphate linked moiety X)-type motif 5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1858232
    NCBI Gene: 53893
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:5849839-5875631 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 3.62 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    662 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1858232
 protein coding gene Chr2:5849830-5876706 (+)
129S1/SvImJ MGP_129S1SvImJ_G0025324
 protein coding gene Chr2:2977315-3005487 (+)
A/J MGP_AJ_G0025301
 protein coding gene Chr2:2837675-2864546 (+)
AKR/J MGP_AKRJ_G0025269
 protein coding gene Chr2:2920653-2948673 (+)
BALB/cJ MGP_BALBcJ_G0025297
 protein coding gene Chr2:2816452-2843148 (+)
C3H/HeJ MGP_C3HHeJ_G0025057
 protein coding gene Chr2:2880961-2907658 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025739
 protein coding gene Chr2:3053470-3082530 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0023153
 protein coding gene Chr2:2647381-2674041 (+)
CAST/EiJ MGP_CASTEiJ_G0024520
 protein coding gene Chr2:2923495-2950867 (+)
CBA/J MGP_CBAJ_G0025036
 protein coding gene Chr2:3189051-3217835 (+)
DBA/2J MGP_DBA2J_G0025168
 protein coding gene Chr2:2781124-2807802 (+)
FVB/NJ MGP_FVBNJ_G0025130
 protein coding gene Chr2:2775965-2807920 (+)
LP/J MGP_LPJ_G0025254
 protein coding gene Chr2:2924466-2951092 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0025162
 protein coding gene Chr2:3036164-3062811 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025797
 protein coding gene Chr2:2912224-2942383 (+)
PWK/PhJ MGP_PWKPhJ_G0024271
 protein coding gene Chr2:2775755-2802466 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024071
 protein coding gene Chr2:2897271-2923580 (+)
WSB/EiJ MGP_WSBEiJ_G0024590
 protein coding gene Chr2:2946535-2973665 (+)



Homology
more
  • Human Ortholog
    NUDT5, nudix hydrolase 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NUDT5, nudix hydrolase 5
  • Synonyms
    hNUDT5, YSA1, YSA1H, YSAH1
  • Links
    NCBI Gene ID: 11164
    neXtProt AC: NX_Q9UKK9
    UniProt: Q9UKK9

  • Chr Location
    10p14; chr10:12165330-12195891 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    32
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    835
  • Tissues
    120
  • cDNA Data
    82
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 53893 NCBI Gene Model | MGI Sequence Detail 25793 C57BL/6J ±  kb
    transcript NM_001418411 RefSeq | MGI Sequence Detail 3558 C57BL/6  
    polypeptide Q9JKX6 UniProt | EBI | MGI Sequence Detail 218 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 85
      cDNA 84
      Primer pair 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 14
    • Earliest
      J:61326 Yang H, et al., Cloning and characterization of a new member of the Nudix hydrolases from human and mouse. J Biol Chem. 2000 Mar 24;275(12):8844-53
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory