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Gpa33 Gene Detail
Summary
  • Symbol
    Gpa33
  • Name
    glycoprotein A33 transmembrane
  • Synonyms
    2010310L10Rik, 2210401D16Rik, A33 antigen
  • Feature Type
    protein coding gene
  • IDs
    MGI:1891703
    NCBI Gene: 59290
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:165957807-165994079 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 73.49 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1400 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1891703
 protein coding gene Chr1:165957790-165994079 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016701
 protein coding gene Chr1:171652187-171694178 (+)
A/J MGP_AJ_G0016682
 protein coding gene Chr1:164659208-164698118 (+)
AKR/J MGP_AKRJ_G0016648
 protein coding gene Chr1:169629581-169667308 (+)
BALB/cJ MGP_BALBcJ_G0016643
 protein coding gene Chr1:165135737-165176040 (+)
C3H/HeJ MGP_C3HHeJ_G0016467
 protein coding gene Chr1:169852217-169891451 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017104
 protein coding gene Chr1:177401278-177441924 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014813
 protein coding gene Chr1:156530287-156565537 (+)
CAST/EiJ MGP_CASTEiJ_G0016047
 protein coding gene Chr1:169448729-169487248 (+)
CBA/J MGP_CBAJ_G0016442
 protein coding gene Chr1:183716928-183760488 (+)
DBA/2J MGP_DBA2J_G0016548
 protein coding gene Chr1:163525569-163563147 (+)
FVB/NJ MGP_FVBNJ_G0016546
 protein coding gene Chr1:161961669-161999031 (+)
LP/J MGP_LPJ_G0016619
 protein coding gene Chr1:172732918-172773865 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016571
 protein coding gene Chr1:191163811-191203791 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017140
 protein coding gene Chr1:169494868-169533348 (+)
PWK/PhJ MGP_PWKPhJ_G0015833
 protein coding gene Chr1:162731510-162772247 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015620
 protein coding gene Chr1:168337317-168373677 (+)
WSB/EiJ MGP_WSBEiJ_G0016109
 protein coding gene Chr1:169632609-169671972 (+)



Homology
more
  • Human Ortholog
    GPA33, glycoprotein A33
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPA33, glycoprotein A33
  • Synonyms
    A33
  • Links
    NCBI Gene ID: 10223
    neXtProt AC: NX_Q99795
    UniProt: Q99795

  • Chr Location
    1q24.1; chr1:167052836-167166479 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    20 phenotypes from 2 alleles in 3 genetic backgrounds
    2 phenotypes from multigenic genotypes
    23 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased susceptibility to induced colitis and impaired oral tolerance to ovalbumin.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    935
  • Tissues
    82
  • cDNA Data
    51
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000000544 Ensembl Gene Model | MGI Sequence Detail 36273 C57BL/6J ±  kb
    transcript ENSMUST00000060833 Ensembl | MGI Sequence Detail 2515 Not Applicable  
    polypeptide ENSMUSP00000060147 Ensembl | MGI Sequence Detail 319 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 52
      cDNA 52

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1921497, MGI:1923785, MGI:2138634
    References
    more
    • Summaries
      All 48
      Developmental Gene Expression 4
      Gene Ontology 2
      Phenotypes 23
    • Earliest
      J:64884 Johnstone CN, et al., Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2000 Sep;279(3):G500-10
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory