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Dimt1 Gene Detail
Summary
  • Symbol
    Dimt1
  • Name
    DIM1 rRNA methyltransferase and ribosome maturation factor
  • Synonyms
    1500031M22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913504
    NCBI Gene: 66254
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:107083635-107096732 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 58.06 cM, cytoband D1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    303 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913504
 protein coding gene Chr13:107083635-107097833 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020917
 protein coding gene Chr13:109141345-109154501 (+)
A/J MGP_AJ_G0020868
 protein coding gene Chr13:104890869-104905619 (+)
AKR/J MGP_AKRJ_G0020843
 protein coding gene Chr13:108065456-108078600 (+)
BALB/cJ MGP_BALBcJ_G0020868
 protein coding gene Chr13:105592101-105604069 (+)
C3H/HeJ MGP_C3HHeJ_G0020657
 protein coding gene Chr13:107829517-107842805 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021302
 protein coding gene Chr13:112450789-112465938 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018872
 protein coding gene Chr13:100326283-100339595 (+)
CAST/EiJ MGP_CASTEiJ_G0020176
 protein coding gene Chr13:107326315-107339319 (+)
CBA/J MGP_CBAJ_G0020619
 protein coding gene Chr13:116774525-116785040 (+)
DBA/2J MGP_DBA2J_G0020743
 protein coding gene Chr13:104651342-104665297 (+)
FVB/NJ MGP_FVBNJ_G0020725
 protein coding gene Chr13:103309222-103320948 (+)
LP/J MGP_LPJ_G0020817
 protein coding gene Chr13:109222279-109237031 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020753
 protein coding gene Chr13:117241026-117255741 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021341
 protein coding gene Chr13:107491734-107505678 (+)
PWK/PhJ MGP_PWKPhJ_G0019929
 protein coding gene Chr13:103308692-103322622 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019751
 protein coding gene Chr13:103753286-103766149 (+)
WSB/EiJ MGP_WSBEiJ_G0020234
 protein coding gene Chr13:108047794-108060861 (+)



Homology
more
  • Human Ortholog
    DIMT1, DIM1 rRNA methyltransferase and ribosome maturation factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DIMT1, DIM1 rRNA methyltransferase and ribosome maturation factor
  • Synonyms
    DIM1, DIMT1L, HSA9761, HUSSY5
  • Links
    NCBI Gene ID: 27292
    neXtProt AC: NX_Q9UNQ2
    UniProt: Q9UNQ2

  • Chr Location
    5q12.1; chr5:62347284-62403943 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    727
  • Tissues
    1
  • cDNA Data
    43
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000021692 Ensembl Gene Model | MGI Sequence Detail 13098 C57BL/6J ±  kb
transcript ENSMUST00000022203 Ensembl | MGI Sequence Detail 2051 Not Applicable  
polypeptide ENSMUSP00000022203 Ensembl | MGI Sequence Detail 313 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000031100 probable dimethyladenosine transferase
    (term hierarchy)
  • EC
    2.1.1.-, 2.1.1.183
  • InterPro Domains
    IPR011530 Ribosomal RNA adenine dimethylase
    IPR020596 Ribosomal RNA adenine methylase transferase, conserved site
    IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal
    IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
  • GlyGen
    Q9D0D4 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 5
Other
Accession IDs
less
MGI:2140530
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory