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Dhrs7 Gene Detail
Summary
  • Symbol
    Dhrs7
  • Name
    dehydrogenase/reductase 7
  • Synonyms
    2310016E22Rik, 5730564L20Rik, dehydrogenase/reductase (SDR family) member 7, retDSR4, retSDR4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913625
    NCBI Gene: 66375
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:72697127-72711678 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 30.23 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    584 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913625
 protein coding gene Chr12:72697127-72711683 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019828
 protein coding gene Chr12:72485505-72502864 (-)
A/J MGP_AJ_G0019786
 protein coding gene Chr12:69788476-69803995 (-)
AKR/J MGP_AKRJ_G0019761
 protein coding gene Chr12:71906477-71922950 (-)
BALB/cJ MGP_BALBcJ_G0019766
 protein coding gene Chr12:70273899-70288554 (-)
C3H/HeJ MGP_C3HHeJ_G0019571
 protein coding gene Chr12:72333371-72350174 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020218
 protein coding gene Chr12:74768262-74786409 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017837
 protein coding gene Chr12:67254343-67269321 (-)
CAST/EiJ MGP_CASTEiJ_G0019123
 protein coding gene Chr12:67108130-67128566 (-)
CBA/J MGP_CBAJ_G0019541
 protein coding gene Chr12:77577600-77597145 (-)
DBA/2J MGP_DBA2J_G0019657
 protein coding gene Chr12:69685505-69704147 (-)
FVB/NJ MGP_FVBNJ_G0019644
 protein coding gene Chr12:68546220-68560551 (-)
LP/J MGP_LPJ_G0019729
 protein coding gene Chr12:72491207-72505549 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019683
 protein coding gene Chr12:80749598-80765603 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020253
 protein coding gene Chr12:71380546-71397267 (-)
PWK/PhJ MGP_PWKPhJ_G0018887
 protein coding gene Chr12:63934882-63993758 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018683
 protein coding gene Chr12:65793773-65810771 (-)
WSB/EiJ MGP_WSBEiJ_G0019174
 protein coding gene Chr12:71977737-71995248 (-)



Homology
more
  • Human Ortholog
    DHRS7, dehydrogenase/reductase 7
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DHRS7, dehydrogenase/reductase 7
  • Synonyms
    CGI-86, retDSR4, retSDR4, SDR34C1
  • Links
    NCBI Gene ID: 51635
    neXtProt AC: NX_Q9Y394
    UniProt: Q9Y394

  • Chr Location
    14q23.1; chr14:60144119-60169889 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    721
  • Tissues
    8
  • cDNA Data
    71
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66375 NCBI Gene Model | MGI Sequence Detail 14552 C57BL/6J ±  kb
transcript NM_025522 RefSeq | MGI Sequence Detail 1318 C57BL/6  
polypeptide Q9CXR1 UniProt | EBI | MGI Sequence Detail 338 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000029411 dehydrogenase/reductase SDR family member 7
    (term hierarchy)
  • EC
    1.1.1.-
  • InterPro Domains
    IPR053011 Dehydrogenase/reductase SDR family member 7
    IPR036291 NAD(P)-binding domain superfamily
    IPR020904 Short-chain dehydrogenase/reductase, conserved site
    IPR002347 Short-chain dehydrogenase/reductase SDR
  • GlyGen
    Q9CXR1 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 71
    cDNA 71

    Microarray probesets 5
Other
Accession IDs
less
MGI:1917901, MGI:2145001
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:298694 Rattner A, et al., Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus. Elife. 2020 Oct 21;9:e62766
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory