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Ufsp2 Gene Detail
Summary
  • Symbol
    Ufsp2
  • Name
    UFM1-specific peptidase 2
  • Synonyms
    1810047C23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913679
    NCBI Gene: 192169
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:46428565-46449995 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 25.96 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    777 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913679
 protein coding gene Chr8:46428551-46449995 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033581
 protein coding gene Chr8:45058104-45081264 (+)
A/J MGP_AJ_G0033563
 protein coding gene Chr8:43316210-43337574 (+)
AKR/J MGP_AKRJ_G0033488
 protein coding gene Chr8:44588551-44611153 (+)
BALB/cJ MGP_BALBcJ_G0033560
 protein coding gene Chr8:43496061-43519449 (+)
C3H/HeJ MGP_C3HHeJ_G0033269
 protein coding gene Chr8:45117344-45140661 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034076
 protein coding gene Chr8:46756811-46782353 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031025
 protein coding gene Chr8:39588050-39608992 (+)
CAST/EiJ MGP_CASTEiJ_G0032595
 protein coding gene Chr8:44552340-44578680 (+)
CBA/J MGP_CBAJ_G0033248
 protein coding gene Chr8:48648433-48676672 (+)
DBA/2J MGP_DBA2J_G0033401
 protein coding gene Chr8:43124517-43148087 (+)
FVB/NJ MGP_FVBNJ_G0033342
 protein coding gene Chr8:42621843-42643399 (+)
LP/J MGP_LPJ_G0033489
 protein coding gene Chr8:45062472-45089841 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033387
 protein coding gene Chr8:48720586-48747275 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034094
 protein coding gene Chr8:44749068-44771802 (+)
PWK/PhJ MGP_PWKPhJ_G0032303
 protein coding gene Chr8:42647081-42668718 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032139
 protein coding gene Chr8:43901354-43926479 (+)
WSB/EiJ MGP_WSBEiJ_G0032711
 protein coding gene Chr8:45000385-45025420 (+)



Homology
more
  • Human Ortholog
    UFSP2, UFM1 specific peptidase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UFSP2, UFM1 specific peptidase 2
  • Synonyms
    BHD, C4orf20, DEE106, SEMDDR
  • Links
    NCBI Gene ID: 55325
    neXtProt AC: NX_Q9NUQ7
    UniProt: Q9NUQ7

  • Chr Location
    4q35.1; chr4:185399537-185425979 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with human UFSP2 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    5
  • cDNA Data
    6
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031634 Ensembl Gene Model | MGI Sequence Detail 21431 C57BL/6J ±  kb
transcript ENSMUST00000034051 Ensembl | MGI Sequence Detail 1640 Not Applicable  
polypeptide ENSMUSP00000034051 Ensembl | MGI Sequence Detail 461 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 3
References
more
  • Summaries
    All 34
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory