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Fam136a Gene Detail
Summary
  • Symbol
    Fam136a
  • Name
    family with sequence similarity 136, member A
  • Synonyms
    2010309E21Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913738
    NCBI Gene: 66488
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:86342628-86347040 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 37.69 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    192 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913738
 protein coding gene Chr6:86342453-86347040 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030972
 protein coding gene Chr6:87643419-87648187 (+)
A/J MGP_AJ_G0030938
 protein coding gene Chr6:84263074-84267487 (+)
AKR/J MGP_AKRJ_G0030869
 protein coding gene Chr6:86702147-86706559 (+)
BALB/cJ MGP_BALBcJ_G0030951
 protein coding gene Chr6:84275370-84279782 (+)
C3H/HeJ MGP_C3HHeJ_G0030759
 protein coding gene Chr6:97748985-97753398 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031408
 protein coding gene Chr6:90022293-90026705 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028592
 protein coding gene Chr6:82438932-144518947 (+)
CAST/EiJ MGP_CASTEiJ_G0030060
 protein coding gene Chr6:86769384-86778175 (+)
CBA/J MGP_CBAJ_G0030635
 protein coding gene Chr6:93562566-93572414 (+)
DBA/2J MGP_DBA2J_G0030791
 protein coding gene Chr6:83582884-83587297 (+)
FVB/NJ MGP_FVBNJ_G0030744
 protein coding gene Chr6:82766218-82770631 (+)
LP/J MGP_LPJ_G0030868
 protein coding gene Chr6:87681090-87685503 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030777
 protein coding gene Chr6:97700681-97705094 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031435
 protein coding gene Chr6:86550974-86555386 (+)
PWK/PhJ MGP_PWKPhJ_G0029775
 protein coding gene Chr6:82525468-82529933 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029603
 protein coding gene Chr6:85386538-85389609 (+)
WSB/EiJ MGP_WSBEiJ_G0030141
 protein coding gene Chr6:87002852-87007264 (+)



Homology
more
  • Human Ortholog
    FAM136A, family with sequence similarity 136 member A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM136A, family with sequence similarity 136 member A
  • Links
    NCBI Gene ID: 84908
    neXtProt AC: NX_Q96C01
    UniProt: Q96C01

  • Chr Location
    2p13.3; chr2:70295976-70302067 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit increased susceptibility to age-related hearing loss .
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    854
  • Tissues
    20
  • cDNA Data
    38
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000057497 Ensembl Gene Model | MGI Sequence Detail 4413 C57BL/6J ±  kb
transcript ENSMUST00000071492 Ensembl | MGI Sequence Detail 1643 Not Applicable  
polypeptide ENSMUSP00000071426 Ensembl | MGI Sequence Detail 138 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 38
    cDNA 38

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146199
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory