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Mrpl51 Gene Detail
Summary
  • Symbol
    Mrpl51
  • Name
    mitochondrial ribosomal protein L51
  • Synonyms
    2610511M02Rik, CDA09, HSPC241, Mrp64
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913743
    NCBI Gene: 66493
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:125169163-125171355 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 59.32 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    172 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913743
 protein coding gene Chr6:125168764-125173232 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031290
 protein coding gene Chr6:128526569-128531855 (+)
A/J MGP_AJ_G0031260
 protein coding gene Chr6:123676893-123681520 (+)
AKR/J MGP_AKRJ_G0031188
 protein coding gene Chr6:127053841-127058319 (+)
BALB/cJ MGP_BALBcJ_G0031268
 protein coding gene Chr6:123275356-123279841 (+)
C3H/HeJ MGP_C3HHeJ_G0030991
 protein coding gene Chr6:127125731-127130201 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031724
 protein coding gene Chr6:131907910-131912378 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028873
 protein coding gene Chr6:120883246-120883864 (+)
CAST/EiJ MGP_CASTEiJ_G0030372
 protein coding gene Chr6:127327292-127332692 (+)
CBA/J MGP_CBAJ_G0030952
 protein coding gene Chr6:136967026-136971507 (+)
DBA/2J MGP_DBA2J_G0031108
 protein coding gene Chr6:122608939-122614240 (+)
FVB/NJ MGP_FVBNJ_G0031058
 protein coding gene Chr6:121521706-121527244 (+)
LP/J MGP_LPJ_G0031188
 protein coding gene Chr6:128689902-128694382 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031096
 protein coding gene Chr6:140998648-141003121 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031759
 protein coding gene Chr6:126955333-126959803 (+)
PWK/PhJ MGP_PWKPhJ_G0030087
 protein coding gene Chr6:120851453-120856103 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029916
 protein coding gene Chr6:125031346-125035910 (+)
WSB/EiJ MGP_WSBEiJ_G0030457
 protein coding gene Chr6:127326738-127331210 (+)



Homology
more
  • Human Ortholog
    MRPL51, mitochondrial ribosomal protein L51
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL51, mitochondrial ribosomal protein L51
  • Synonyms
    bMRP64, CDA09, HSPC241, mL51, MRP64
  • Links
    NCBI Gene ID: 51258
    neXtProt AC: NX_Q4U2R6
    UniProt: Q4U2R6

  • Chr Location
    12p13.31; chr12:6491886-6493841 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    777
  • Tissues
    57
  • cDNA Data
    131
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 66493 NCBI Gene Model | MGI Sequence Detail 2193 C57BL/6J ±  kb
    transcript NM_025595 RefSeq | MGI Sequence Detail 1515 C57BL/6  
    polypeptide Q9CPY1 UniProt | EBI | MGI Sequence Detail 128 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 134
      cDNA 133
      Primer pair 1

      Microarray probesets 5
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 3
      Gene Ontology 7
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory