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Gtf3a Gene Detail
Summary
  • Symbol
    Gtf3a
  • Name
    general transcription factor III A
  • Synonyms
    2010015D03Rik, 2610111I01Rik, 5330403M05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913846
    NCBI Gene: 66596
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:146885467-146892424 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 86.57 cM, cytoband G2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    351 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913846
 protein coding gene Chr5:146885467-146892424 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030381
 protein coding gene Chr5:152569838-152576795 (+)
A/J MGP_AJ_G0030354
 protein coding gene Chr5:146111014-146117956 (+)
AKR/J MGP_AKRJ_G0030281
 protein coding gene Chr5:150598577-150605548 (+)
BALB/cJ MGP_BALBcJ_G0030363
 protein coding gene Chr5:147321872-147328814 (+)
C3H/HeJ MGP_C3HHeJ_G0030077
 protein coding gene Chr5:151552035-151558977 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030818
 protein coding gene Chr5:158144952-158151909 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028031
 protein coding gene Chr5:140524499-140531452 (+)
CAST/EiJ MGP_CASTEiJ_G0029479
 protein coding gene Chr5:151116056-151122989 (+)
CBA/J MGP_CBAJ_G0030055
 protein coding gene Chr5:164731417-164738388 (+)
DBA/2J MGP_DBA2J_G0030199
 protein coding gene Chr5:145793186-145800128 (+)
FVB/NJ MGP_FVBNJ_G0030153
 protein coding gene Chr5:144981663-144988629 (+)
LP/J MGP_LPJ_G0030286
 protein coding gene Chr5:153264663-153271620 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030189
 protein coding gene Chr5:167049411-167056368 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030848
 protein coding gene Chr5:150504510-150511481 (+)
PWK/PhJ MGP_PWKPhJ_G0029193
 protein coding gene Chr5:144871043-144878094 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029029
 protein coding gene Chr5:147810726-147817696 (+)
WSB/EiJ MGP_WSBEiJ_G0029556
 protein coding gene Chr5:151290490-151297432 (+)



Homology
more
  • Human Ortholog
    GTF3A, general transcription factor IIIA
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GTF3A, general transcription factor IIIA
  • Synonyms
    AP2, TFIIIA
  • Links
    NCBI Gene ID: 2971
    neXtProt AC: NX_Q92664
    UniProt: Q92664

  • Chr Location
    13q12.2; chr13:27424619-27435823 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    848
  • Tissues
    56
  • cDNA Data
    74
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66596 NCBI Gene Model | MGI Sequence Detail 6958 C57BL/6J ±  kb
transcript NM_025652 RefSeq | MGI Sequence Detail 1315 C57BL/6  
polypeptide Q8VHT7 UniProt | EBI | MGI Sequence Detail 364 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 76
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:1919733, MGI:1923924
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:190636 Wiese CB, et al., A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory