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Rcc1 Gene Detail
Summary
  • Symbol
    Rcc1
  • Name
    regulator of chromosome condensation 1
  • Synonyms
    4931417M11Rik, Chc1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1913989
    NCBI Gene: 100088
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:132059230-132073061 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 65.20 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    432 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1913989
 protein coding gene Chr4:132059230-132080916 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028869
 protein coding gene Chr4:134474612-134499495 (-)
A/J MGP_AJ_G0028828
 protein coding gene Chr4:128888448-128910103 (-)
AKR/J MGP_AKRJ_G0028781
 protein coding gene Chr4:132507343-132529356 (-)
BALB/cJ MGP_BALBcJ_G0028851
 protein coding gene Chr4:129499091-129522227 (-)
C3H/HeJ MGP_C3HHeJ_G0028565
 protein coding gene Chr4:132765774-132790922 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029293
 protein coding gene Chr4:139327490-139349053 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026564
 protein coding gene Chr4:121965225-121985947 (-)
CAST/EiJ MGP_CASTEiJ_G0027998
 protein coding gene Chr4:130840613-130867131 (-)
CBA/J MGP_CBAJ_G0028531
 protein coding gene Chr4:142899470-142924193 (-)
DBA/2J MGP_DBA2J_G0028680
 protein coding gene Chr4:129311148-129333242 (-)
FVB/NJ MGP_FVBNJ_G0028647
 protein coding gene Chr4:128159656-128181946 (-)
LP/J MGP_LPJ_G0028781
 protein coding gene Chr4:134631635-134655445 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028673
 protein coding gene Chr4:147492499-147514199 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029331
 protein coding gene Chr4:132911570-132934127 (-)
PWK/PhJ MGP_PWKPhJ_G0027719
 protein coding gene Chr4:125990985-126013663 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027545
 protein coding gene Chr4:128783972-128807303 (-)
WSB/EiJ MGP_WSBEiJ_G0028078
 protein coding gene Chr4:133097515-133119140 (-)



Homology
more
  • Human Ortholog
    RCC1, regulator of chromosome condensation 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RCC1, regulator of chromosome condensation 1
  • Synonyms
    CHC1, RCC1-I
  • Links
    NCBI Gene ID: 1104
    neXtProt AC: NX_P18754
    UniProt: P18754

  • Chr Location
    1p35.3; chr1:28505943-28539300 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    31
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    794
  • Tissues
    53
  • cDNA Data
    144
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 100088 NCBI Gene Model | MGI Sequence Detail 13832 C57BL/6J ±  kb
transcript NM_001197082 RefSeq | MGI Sequence Detail 2332 C57BL/6  
polypeptide Q8VE37 UniProt | EBI | MGI Sequence Detail 421 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000013833 regulator of chromosome condensation
    (term hierarchy)
  • InterPro Domains
    IPR051553 Ran GTPase-activating
    IPR009091 Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II
    IPR000408 Regulator of chromosome condensation, RCC1
Molecular
Reagents
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  • All nucleic 145
    cDNA 144
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140246
References
more
  • Summaries
    All 47
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 15
  • Earliest
    J:34518 Kerr SM, et al., Ott, a mouse X-linked multigene family expressed specifically during meiosis. Hum Mol Genet. 1996 Aug;5(8):1139-48
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory