About   Help   FAQ
Hint3 Gene Detail
Summary
  • Symbol
    Hint3
  • Name
    histidine triad nucleotide binding protein 3
  • Synonyms
    0610010I17Rik, HINT4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914097
    NCBI Gene: 66847
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:30479191-30499526 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 17.10 cM, cytoband A4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    576 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914097
 protein coding gene Chr10:30479191-30505628 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017117
 protein coding gene Chr10:28817095-28827433 (-)
A/J MGP_AJ_G0017094
 protein coding gene Chr10:27974458-27984767 (-)
AKR/J MGP_AKRJ_G0017054
 protein coding gene Chr10:28414595-28424931 (-)
BALB/cJ MGP_BALBcJ_G0017057
 protein coding gene Chr10:28053869-28064215 (-)
C3H/HeJ MGP_C3HHeJ_G0016877
 protein coding gene Chr10:28682256-28692607 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017515
 protein coding gene Chr10:29673779-29686622 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015213
 protein coding gene Chr10:26418104-26427824 (-)
CAST/EiJ MGP_CASTEiJ_G0016456
 protein coding gene Chr10:28742375-28756258 (-)
CBA/J MGP_CBAJ_G0016851
 protein coding gene Chr10:31092333-31102521 (-)
DBA/2J MGP_DBA2J_G0016956
 protein coding gene Chr10:27646796-27657006 (-)
FVB/NJ MGP_FVBNJ_G0016951
 protein coding gene Chr10:27263459-27274962 (-)
LP/J MGP_LPJ_G0017033
 protein coding gene Chr10:28830233-28840407 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016981
 protein coding gene Chr10:31291994-31302332 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017551
 protein coding gene Chr10:28327446-28338235 (-)
PWK/PhJ MGP_PWKPhJ_G0016238
 protein coding gene Chr10:27415705-27426904 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016022
 protein coding gene Chr10:28263236-28276890 (-)
WSB/EiJ MGP_WSBEiJ_G0016519
 protein coding gene Chr10:28462416-28476021 (-)



Homology
more
  • Human Ortholog
    HINT3, histidine triad nucleotide binding protein 3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    HINT3, histidine triad nucleotide binding protein 3
  • Synonyms
    HINT4
  • Links
    NCBI Gene ID: 135114
    neXtProt AC: NX_Q9NQE9
    UniProt: Q9NQE9

  • Chr Location
    6q22.32; chr6:125956770-125980244 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    726
  • Tissues
    8
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66847 NCBI Gene Model | MGI Sequence Detail 20336 C57BL/6J ±  kb
transcript NM_025798 RefSeq | MGI Sequence Detail 696 C57BL/6  
polypeptide Q9CPS6 UniProt | EBI | MGI Sequence Detail 165 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 8
    Primer pair 2

    Microarray probesets 4
Other
Accession IDs
less
MGI:2143774
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:298016 Cortes-Montero E, et al., The Axonal Motor Neuropathy-Related HINT1 Protein Is a Zinc- and Calmodulin-Regulated Cysteine SUMO Protease. Antioxid Redox Signal. 2019 Sep 1;31(7):503-520
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory