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Pxdc1 Gene Detail
Summary
  • Symbol
    Pxdc1
  • Name
    PX domain containing 1
  • Synonyms
    1300014I06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914145
    NCBI Gene: 66895
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:34811823-34836664 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 14.16 cM, cytoband A4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1076 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914145
 protein coding gene Chr13:34811817-34837469 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020451
 protein coding gene Chr13:32756288-32780855 (-)
A/J MGP_AJ_G0020405
 protein coding gene Chr13:31772211-31796879 (-)
AKR/J MGP_AKRJ_G0020383
 protein coding gene Chr13:32537676-32562301 (-)
BALB/cJ MGP_BALBcJ_G0020401
 protein coding gene Chr13:31845782-31870400 (-)
C3H/HeJ MGP_C3HHeJ_G0020200
 protein coding gene Chr13:32470604-32495310 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020834
 protein coding gene Chr13:33820896-33845458 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018421
 protein coding gene Chr13:30085007-30110196 (-)
CAST/EiJ MGP_CASTEiJ_G0019715
 protein coding gene Chr13:32101773-32152454 (-)
CBA/J MGP_CBAJ_G0020161
 protein coding gene Chr13:35301581-35326262 (-)
DBA/2J MGP_DBA2J_G0020283
 protein coding gene Chr13:31313799-31338600 (-)
FVB/NJ MGP_FVBNJ_G0020262
 protein coding gene Chr13:30876697-30901450 (-)
LP/J MGP_LPJ_G0020358
 protein coding gene Chr13:32987620-33012292 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020292
 protein coding gene Chr13:35500732-35525383 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020877
 protein coding gene Chr13:32183213-32208022 (-)
PWK/PhJ MGP_PWKPhJ_G0019470
 protein coding gene Chr13:31421060-31464003 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019297
 protein coding gene Chr13:30800187-30855953 (-)
WSB/EiJ MGP_WSBEiJ_G0019777
 protein coding gene Chr13:32549863-32574624 (-)



Homology
more
  • Human Ortholog
    PXDC1, PX domain containing 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PXDC1, PX domain containing 1
  • Synonyms
    C6orf145
  • Links
    NCBI Gene ID: 221749
    neXtProt AC: NX_Q5TGL8
    UniProt: Q5TGL8

  • Chr Location
    6p25.2; chr6:3722614-3751713 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Radiation induced
    1
  • Targeted
    4
  • Genomic Mutations
    2 involving Pxdc1
  • Find Mice (IMSR)
    21 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    40
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 66895 NCBI Gene Model | MGI Sequence Detail 24842 C57BL/6J ±  kb
transcript NR_168613 RefSeq | MGI Sequence Detail 2027 C57BL/6  
polypeptide Q8JZU6 UniProt | EBI | MGI Sequence Detail 231 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 40
    cDNA 40

    Microarray probesets 4
References
more
  • Summaries
    All 37
    Gene Ontology 1
    Phenotypes 16
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory