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Lsm14a Gene Detail
Summary
  • Symbol
    Lsm14a
  • Name
    LSM14A mRNA processing body assembly factor
  • Synonyms
    2700023B17Rik, Tral
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914320
    NCBI Gene: 67070
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:34043569-34089134 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 19.56 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1160 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914320
 protein coding gene Chr7:34043569-34092740 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032077
 protein coding gene Chr7:33616308-33672946 (-)
A/J MGP_AJ_G0032057
 protein coding gene Chr7:32787066-32836912 (-)
AKR/J MGP_AKRJ_G0031990
 protein coding gene Chr7:33558381-33609954 (-)
BALB/cJ MGP_BALBcJ_G0032064
 protein coding gene Chr7:33076654-33125741 (-)
C3H/HeJ MGP_C3HHeJ_G0031781
 protein coding gene Chr7:34444926-34504400 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032541
 protein coding gene Chr7:35328038-35381200 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029574
 protein coding gene Chr7:33517804-33568657 (-)
CAST/EiJ MGP_CASTEiJ_G0031116
 protein coding gene Chr7:25566281-25617734 (-)
CBA/J MGP_CBAJ_G0031749
 protein coding gene Chr7:36419657-36481101 (-)
DBA/2J MGP_DBA2J_G0031901
 protein coding gene Chr7:32633675-32683110 (-)
FVB/NJ MGP_FVBNJ_G0031856
 protein coding gene Chr7:32545651-32595076 (-)
LP/J MGP_LPJ_G0031978
 protein coding gene Chr7:33985024-34036434 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031894
 protein coding gene Chr7:35484473-35540455 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032556
 protein coding gene Chr7:33091791-33142776 (-)
PWK/PhJ MGP_PWKPhJ_G0030838
 protein coding gene Chr7:25944467-25997135 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030673
 protein coding gene Chr7:22653883-22706693 (-)
WSB/EiJ MGP_WSBEiJ_G0031226
 protein coding gene Chr7:33631771-33684901 (-)



Homology
more
  • Human Ortholog
    LSM14A, LSM14A mRNA processing body assembly factor
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LSM14A, LSM14A mRNA processing body assembly factor
  • Synonyms
    C19orf13, FAM61A, RAP55, RAP55A
  • Links
    NCBI Gene ID: 26065
    neXtProt AC: NX_Q8ND56
    UniProt: Q8ND56

  • Chr Location
    19q13.11; chr19:34172504-34229288 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    732
  • Tissues
    13
  • cDNA Data
    12
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67070 NCBI Gene Model | MGI Sequence Detail 45566 C57BL/6J ±  kb
    transcript NM_025948 RefSeq | MGI Sequence Detail 3464 C57BL/6  
    polypeptide Q8K2F8 UniProt | EBI | MGI Sequence Detail 462 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 12

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2141809, MGI:2142123
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 2
      Gene Ontology 7
      Phenotypes 14
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory