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Zcrb1 Gene Detail
Summary
  • Symbol
    Zcrb1
  • Name
    zinc finger CCHC-type and RNA binding motif 1
  • Synonyms
    2700088M22Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914447
    NCBI Gene: 67197
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:93283987-93296218 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 47.53 cM, cytoband F1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    458 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914447
 protein coding gene Chr15:93283978-93296218 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022255
 protein coding gene Chr15:94798829-94811053 (-)
A/J MGP_AJ_G0022214
 protein coding gene Chr15:91135684-91147907 (-)
AKR/J MGP_AKRJ_G0022189
 protein coding gene Chr15:93863061-93875291 (-)
BALB/cJ MGP_BALBcJ_G0022220
 protein coding gene Chr15:91256462-91268695 (-)
C3H/HeJ MGP_C3HHeJ_G0021990
 protein coding gene Chr15:93865397-93877620 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022665
 protein coding gene Chr15:98260243-98272469 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020191
 protein coding gene Chr15:87178552-87191615 (-)
CAST/EiJ MGP_CASTEiJ_G0021512
 protein coding gene Chr15:94692790-94703634 (-)
CBA/J MGP_CBAJ_G0021957
 protein coding gene Chr15:101577310-101589533 (-)
DBA/2J MGP_DBA2J_G0022084
 protein coding gene Chr15:90561501-90573724 (-)
FVB/NJ MGP_FVBNJ_G0022063
 protein coding gene Chr15:89581702-89593925 (-)
LP/J MGP_LPJ_G0022155
 protein coding gene Chr15:94907655-94919880 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022083
 protein coding gene Chr15:105934250-105946472 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022680
 protein coding gene Chr15:93935518-93947735 (-)
PWK/PhJ MGP_PWKPhJ_G0021253
 protein coding gene Chr15:90612705-90625137 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021087
 protein coding gene Chr15:93679570-93692492 (-)
WSB/EiJ MGP_WSBEiJ_G0021561
 protein coding gene Chr15:94429582-94441842 (-)



Homology
more
  • Human Ortholog
    ZCRB1, zinc finger CCHC-type and RNA binding motif containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZCRB1, zinc finger CCHC-type and RNA binding motif containing 1
  • Synonyms
    MADP-1, MADP1, RBM36, SNRNP31, ZCCHC19
  • Links
    NCBI Gene ID: 85437
    neXtProt AC: NX_Q8TBF4
    UniProt: Q8TBF4

  • Chr Location
    12q12; chr12:42312086-42326257 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    728
  • Tissues
    22
  • cDNA Data
    48
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67197 NCBI Gene Model | MGI Sequence Detail 12232 C57BL/6J ±  kb
    transcript NM_026025 RefSeq | MGI Sequence Detail 888 C57BL/6  
    polypeptide Q9CZ96 UniProt | EBI | MGI Sequence Detail 217 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000029888 zinc finger CCHC-type and RNA-binding motif-containing protein 1
      (term hierarchy)
    • InterPro Domains
      IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
      IPR035979 RNA-binding domain superfamily
      IPR000504 RNA recognition motif domain
      IPR003954 RNA recognition motif domain, eukaryote
      IPR034219 ZCRB1, RNA recognition motif
      IPR001878 Zinc finger, CCHC-type
      IPR044598 Zinc finger CCHC-type and RNA-binding motif-containing protein 1
      IPR036875 Zinc finger, CCHC-type superfamily
    Molecular
    Reagents
    less
    • All nucleic 49
      cDNA 48
      Primer pair 1

      Microarray probesets 5
    References
    more
    • Summaries
      All 54
      Developmental Gene Expression 2
      Diseases 1
      Gene Ontology 6
      Phenotypes 27
    • Earliest
      J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory