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Ceacam12 Gene Detail
Summary
  • Symbol
    Ceacam12
  • Name
    CEA cell adhesion molecule 12
  • Synonyms
    1600031J20Rik, Ceacam12-C1, Ceacam12-C3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914565
    NCBI Gene: 67315
  • Member of
    Cea cluster
  • Alliance
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:17799854-17811911 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 9.15 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    511 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914565
protein coding gene Chr7:17799854-17811911 (+)
129S1/SvImJ MGP_129S1SvImJ_G0031736
protein coding gene Chr7:15886039-15898130 (+)
A/J MGP_AJ_G0031708
protein coding gene Chr7:15563559-15575614 (+)
AKR/J MGP_AKRJ_G0031633
protein coding gene Chr7:15944710-15956765 (+)
BALB/cJ MGP_BALBcJ_G0031715
protein coding gene Chr7:15798058-15810113 (+)
C3H/HeJ MGP_C3HHeJ_G0031437
protein coding gene Chr7:16245611-16257702 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032181
protein coding gene Chr7:16713583-16725640 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0030788
protein coding gene Chr7:12752250-12760828 (+)
CBA/J MGP_CBAJ_G0031396
protein coding gene Chr7:17283088-17295169 (+)
DBA/2J MGP_DBA2J_G0031552
protein coding gene Chr7:15479809-15491864 (+)
FVB/NJ MGP_FVBNJ_G0031508
protein coding gene Chr7:15450881-15463061 (+)
LP/J MGP_LPJ_G0031637
protein coding gene Chr7:16135148-16147239 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031543
protein coding gene Chr7:17198921-17210978 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032210
protein coding gene Chr7:15711300-15723355 (+)
PWK/PhJ MGP_PWKPhJ_G0030511
protein coding gene Chr7:12868066-12880172 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030338
protein coding gene Chr7:10556258-10569159 (+)
WSB/EiJ MGP_WSBEiJ_G0030884
protein coding gene Chr7:15826191-15838248 (+)



Homology
more
  • Human Ortholog
    CEACAM4, CEA cell adhesion molecule 4
  • Vertebrate Orthologs
    20
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEACAM4, CEA cell adhesion molecule 4
  • Synonyms
    CGM7, CGM7_HUMAN, NCA
  • Links
    NCBI Gene ID: 1089
    neXtProt AC: NX_O75871
    UniProt: O75871

  • Chr Location
    19q13.2; chr19:41613436-41627074 (-)  GRCh38

  • Human Ortholog
    PSG5, pregnancy specific beta-1-glycoprotein 5
  • Synonyms
    FL-NCA-3, PSG
  • Links
    NCBI Gene ID: 5673
    neXtProt AC: NX_Q15238
    UniProt: Q15238

  • Chr Location
    19q13.31; chr19:43166256-43186536 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67315 NCBI Gene Model | MGI Sequence Detail 12058 C57BL/6J ±  kb
transcript NM_001162524 RefSeq | MGI Sequence Detail 1875 C57BL/6  
polypeptide NP_080363 RefSeq | MGI Sequence Detail 300 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR050831 Carcinoembryonic antigen-related cell adhesion
    IPR036179 Immunoglobulin-like domain superfamily
    IPR013783 Immunoglobulin-like fold
    IPR013106 Immunoglobulin V-set domain
  • GlyGen
    Q3UKP4 2 sites, 1 O-linked glycan (2 sites)
Molecular
Reagents
less
  • All nucleic 37
    cDNA 36
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 26
    Developmental Gene Expression 2
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:122 Wolfe HG, et al., Hemoglobins in mice. Segregation of genetic factors affecting electrophoretic mobility and solubility. J Hered. 1963 May-Jun;54:107-112
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory