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Carnmt1 Gene Detail
Summary
  • Symbol
    Carnmt1
  • Name
    carnosine N-methyltransferase 1
  • Synonyms
    2410127L17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914633
    NCBI Gene: 67383
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:18648128-18684564 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 13.18 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1095 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914633
 protein coding gene Chr19:18648099-18684565 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024968
 protein coding gene Chr19:16550877-16586771 (+)
A/J MGP_AJ_G0024945
 protein coding gene Chr19:15619902-15654114 (+)
AKR/J MGP_AKRJ_G0024915
 protein coding gene Chr19:16238872-16274147 (+)
BALB/cJ MGP_BALBcJ_G0024944
 protein coding gene Chr19:15651366-15685831 (+)
C3H/HeJ MGP_C3HHeJ_G0024702
 protein coding gene Chr19:16181815-16216781 (+)
C57BL/6NJ MGP_C57BL6NJ_G0025386
 protein coding gene Chr19:17141214-17180668 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0022805
 protein coding gene Chr19:15991004-16022913 (+)
CAST/EiJ MGP_CASTEiJ_G0024170
 protein coding gene Chr19:15818973-15857946 (+)
CBA/J MGP_CBAJ_G0024680
 protein coding gene Chr19:17764940-17804094 (+)
DBA/2J MGP_DBA2J_G0024812
 protein coding gene Chr19:15648476-15683903 (+)
FVB/NJ MGP_FVBNJ_G0024773
 protein coding gene Chr19:15565920-15599649 (+)
LP/J MGP_LPJ_G0024896
 protein coding gene Chr19:16521900-16557709 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0024800
 protein coding gene Chr19:17636085-17680922 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0025441
 protein coding gene Chr19:16176701-16214444 (+)
PWK/PhJ MGP_PWKPhJ_G0023919
 protein coding gene Chr19:15194158-15229736 (+)
SPRET/EiJ MGP_SPRETEiJ_G0023724
 protein coding gene Chr19:15464897-15503796 (+)
WSB/EiJ MGP_WSBEiJ_G0024238
 protein coding gene Chr19:16223653-16259256 (+)



Homology
more
  • Human Ortholog
    CARNMT1, carnosine N-methyltransferase 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CARNMT1, carnosine N-methyltransferase 1
  • Synonyms
    C9orf41, UPF0586
  • Links
    NCBI Gene ID: 138199
    neXtProt AC: NX_Q8N4J0
    UniProt: Q8N4J0

  • Chr Location
    9q21.13; chr9:74980790-75028430 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Micr homozygous for a null or catalytically inactive allele die between E13.5 and E15.5.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    21
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    9
  • cDNA Data
    11
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024726 Ensembl Gene Model | MGI Sequence Detail 36437 C57BL/6J ±  kb
transcript ENSMUST00000025632 Ensembl | MGI Sequence Detail 4518 Not Applicable  
polypeptide ENSMUSP00000025632 Ensembl | MGI Sequence Detail 400 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 7
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:341536 Shimazu T, et al., Histidine N1-position-specific methyltransferase CARNMT1 targets C3H zinc finger proteins and modulates RNA metabolism. Genes Dev. 2023 Aug 1;37(15-16):724-742
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory