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Cby2 Gene Detail
Summary
  • Symbol
    Cby2
  • Name
    chibby family member 2
  • Synonyms
    1700086N05Rik, Nurit, Spert
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915176
    NCBI Gene: 67926
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:75820317-75830556 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 40.23 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    291 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915176
 protein coding gene Chr14:75820274-75830616 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021571
 protein coding gene Chr14:70432016-70441951 (-)
A/J MGP_AJ_G0021529
 protein coding gene Chr14:68842085-68852447 (-)
AKR/J MGP_AKRJ_G0021506
 protein coding gene Chr14:70898796-70910742 (-)
BALB/cJ MGP_BALBcJ_G0021536
 protein coding gene Chr14:68634601-68644251 (-)
C3H/HeJ MGP_C3HHeJ_G0021313
 protein coding gene Chr14:70618475-70628306 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021976
 protein coding gene Chr14:73511647-73522576 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019514
 protein coding gene Chr14:66465344-66474130 (-)
CAST/EiJ MGP_CASTEiJ_G0020830
 protein coding gene Chr14:67280678-67291114 (-)
CBA/J MGP_CBAJ_G0021281
 protein coding gene Chr14:75864941-75873959 (-)
DBA/2J MGP_DBA2J_G0021404
 protein coding gene Chr14:68242914-68252234 (-)
FVB/NJ MGP_FVBNJ_G0021382
 protein coding gene Chr14:67585522-67595139 (-)
LP/J MGP_LPJ_G0021474
 protein coding gene Chr14:71593096-71602340 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021409
 protein coding gene Chr14:74613666-74624762 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021999
 protein coding gene Chr14:70167308-70178372 (-)
PWK/PhJ MGP_PWKPhJ_G0020573
 protein coding gene Chr14:64982111-64991970 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020410
 protein coding gene Chr14:66134075-66143089 (-)
WSB/EiJ MGP_WSBEiJ_G0020883
 protein coding gene Chr14:70505599-70515883 (-)



Homology
more
  • Human Ortholog
    CBY2, chibby family member 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CBY2, chibby family member 2
  • Synonyms
    NURIT, SPERT
  • Links
    NCBI Gene ID: 220082
    neXtProt AC: NX_Q8NA61
    UniProt: Q8NA61

  • Chr Location
    13q14.13; chr13:45702320-45714559 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Males homozygous for a null allele show normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    761
  • Tissues
    16
  • cDNA Data
    18
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000034913 Ensembl Gene Model | MGI Sequence Detail 10240 C57BL/6J ±  kb
transcript ENSMUST00000164082 Ensembl | MGI Sequence Detail 1560 Not Applicable  
polypeptide ENSMUSP00000127439 Ensembl | MGI Sequence Detail 446 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 18
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145677, MGI:6369424
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory