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Ooep Gene Detail
Summary
  • Symbol
    Ooep
  • Name
    oocyte expressed protein
  • Synonyms
    2410146L05Rik, Floped, Moep19
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915218
    NCBI Gene: 67968
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:78284185-78285870 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 43.65 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    153 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915218
protein coding gene Chr9:78283391-78286007 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035067
protein coding gene Chr9:78878743-78881329 (-)
A/J MGP_AJ_G0035048
protein coding gene Chr9:76156709-76159333 (-)
AKR/J MGP_AKRJ_G0034976
protein coding gene Chr9:77959130-77961753 (-)
BALB/cJ MGP_BALBcJ_G0035036
protein coding gene Chr9:75812221-75814843 (-)
C3H/HeJ MGP_C3HHeJ_G0034748
protein coding gene Chr9:78476750-78479364 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035557
protein coding gene Chr9:80999095-81003622 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032466
protein coding gene Chr9:75387775-75390421 (-)
CAST/EiJ MGP_CASTEiJ_G0034067
protein coding gene Chr9:78746966-78749586 (-)
CBA/J MGP_CBAJ_G0034721
protein coding gene Chr9:83865088-83867715 (-)
DBA/2J MGP_DBA2J_G0034879
protein coding gene Chr9:75795773-75798392 (-)
FVB/NJ MGP_FVBNJ_G0034822
protein coding gene Chr9:75025529-75027929 (-)
LP/J MGP_LPJ_G0034960
protein coding gene Chr9:79101921-79104536 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034864
protein coding gene Chr9:85042488-85045111 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035580
protein coding gene Chr9:78120672-78123291 (-)
PWK/PhJ MGP_PWKPhJ_G0033769
protein coding gene Chr9:75986028-75988783 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033606
protein coding gene Chr9:78317437-78320293 (-)
WSB/EiJ MGP_WSBEiJ_G0034182
protein coding gene Chr9:78071630-78074249 (-)



Homology
more
  • Human Ortholog
    OOEP, oocyte expressed protein
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OOEP, oocyte expressed protein
  • Synonyms
    C6orf156, FLOPED, HOEP19, KHDC2
  • Links
    NCBI Gene ID: 441161
    neXtProt AC: NX_A6NGQ2
    UniProt: A6NGQ2

  • Chr Location
    6q13

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 2 alleles in 2 genetic backgrounds
    5 phenotypes from multigenic genotypes
    19 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit female infertility associated with a failure of embryos to progress beyond the 2 cell stage.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67968 NCBI Gene Model | MGI Sequence Detail 1686 C57BL/6J ±  kb
    transcript NM_026480 RefSeq | MGI Sequence Detail 1207 C57BL/6  
    polypeptide Q9CWE6 UniProt | EBI | MGI Sequence Detail 164 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 37
      cDNA 30
      Primer pair 6
      Other 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 56
      Developmental Gene Expression 17
      Gene Ontology 11
      Phenotypes 19
    • Earliest
      J:12013 Russell LB, Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations. Mutat Res. 1971 Jan;11(1):107-23
    • Latest
      J:355487 Han Z, et al., The subcortical maternal complex modulates the cell cycle during early mammalian embryogenesis via 14-3-3. Nat Commun. 2024 Oct 15;15(1):8887

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/12/2024
    MGI 6.24
    The Jackson Laboratory