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Rnaset2a Gene Detail
Summary
  • Symbol
    Rnaset2a
  • Name
    ribonuclease T2A
  • Synonyms
    0610007O07Rik, 4833423A10Rik, 4930532K22Rik, RNASE6PL, Rnaset2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915445
    NCBI Gene: 100037283
  • Alliance
    gene page
Location &
Maps
more
  • Sequence Map
    Chr17:8347412-8367078 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 4.87 cM, cytoband B2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    276 from dbSNP Build 142
  • Strain Annotations
    14
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915445
 protein coding gene Chr17:8334277-8367078 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023128
 protein coding gene Chr17:5585988-5614417 (-)
A/J MGP_AJ_G0023088
 protein coding gene Chr17:4401117-4424267 (+)
AKR/J MGP_AKRJ_G0023061
 protein coding gene Chr17:5282710-5307068 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0022850
 protein coding gene Chr17:4349249-4371202 (+)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0021068
 protein coding gene Chr17:8706653-8726080 (+)
CAST/EiJ MGP_CASTEiJ_G0022375
 protein coding gene Chr17:5528142-5551721 (-)
CBA/J MGP_CBAJ_G0022831
 protein coding gene Chr17:6057398-6082161 (-)
DBA/2J MGP_DBA2J_G0022956
 protein coding gene Chr17:4160776-4183069 (+)
FVB/NJ no annotation
LP/J MGP_LPJ_G0023035
 protein coding gene Chr17:5405406-5428671 (-)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0023565
 protein coding gene Chr17:5562832-5592531 (-)
PWK/PhJ MGP_PWKPhJ_G0022122
 protein coding gene Chr17:4917093-4940256 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021951
 protein coding gene Chr17:4835013-4856133 (-)
WSB/EiJ MGP_WSBEiJ_G0022430
 protein coding gene Chr17:5649510-5672939 (-)



Homology
more
  • Human Ortholog
    RNASET2, ribonuclease T2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RNASET2, ribonuclease T2
  • Synonyms
    bA514O12.3, RNASE6PL
  • Links
    NCBI Gene ID: 8635
    neXtProt AC: NX_O00584
    UniProt: O00584

  • Chr Location
    6q27; chr6:166922113-166957191 (-)  GRCh38
Human Diseases
more
  • Diseases
    7 with human RNASET2 associations

Human Disease Mouse Models
      
IDs
IDs
IDs
IDs
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    6 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    351 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    882
  • Tissues
    111
  • cDNA Data
    11
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 100037283 NCBI Gene Model | MGI Sequence Detail 19667 C57BL/6J ±  kb
transcript NM_001083938 RefSeq | MGI Sequence Detail 999 C57BL/6  
polypeptide C0HKG5 UniProt | EBI | MGI Sequence Detail 259 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 13
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1921009, MGI:1922450, MGI:2147132
References
more
  • Summaries
    All 383
    Developmental Gene Expression 4
    Diseases 6
    Gene Ontology 7
    Phenotypes 351
  • Earliest
    J:30229 Davisson MT, et al., Segmental trisomy as a mouse model for Down syndrome. Prog Clin Biol Res. 1993;384:117-33
  • Latest
    J:354984 Emili M, et al., Reversal of neurodevelopmental impairment and cognitive enhancement by pharmacological intervention with the polyphenol polydatin in a Down syndrome model. Neuropharmacology. 2024 Sep 27;261:110170
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory