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Map1lc3a Gene Detail
Summary
  • Symbol
    Map1lc3a
  • Name
    microtubule-associated protein 1 light chain 3 alpha
  • Synonyms
    1010001H21Rik, 4922501H04Rik, LC3, LC3a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915661
    NCBI Gene: 66734
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:155118284-155119993 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 77.18 cM, cytoband H2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    105 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915661
 protein coding gene Chr2:155118217-155119993 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026731
 protein coding gene Chr2:160085849-160087625 (+)
A/J MGP_AJ_G0026697
 protein coding gene Chr2:153722060-153723836 (+)
AKR/J MGP_AKRJ_G0026668
 protein coding gene Chr2:158183025-158184801 (+)
BALB/cJ MGP_BALBcJ_G0026706
 protein coding gene Chr2:154025234-154027016 (+)
C3H/HeJ MGP_C3HHeJ_G0026449
 protein coding gene Chr2:158542829-158544613 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027155
 protein coding gene Chr2:164777241-164779017 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024525
 protein coding gene Chr2:147227515-147229297 (+)
CAST/EiJ MGP_CASTEiJ_G0025910
 protein coding gene Chr2:158845337-158847110 (+)
CBA/J MGP_CBAJ_G0026426
 protein coding gene Chr2:170775411-170777197 (+)
DBA/2J MGP_DBA2J_G0026563
 protein coding gene Chr2:152906123-152907899 (+)
FVB/NJ MGP_FVBNJ_G0026530
 protein coding gene Chr2:151287136-151288891 (+)
LP/J MGP_LPJ_G0026668
 protein coding gene Chr2:160228887-160230663 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026551
 protein coding gene Chr2:174770049-174771830 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027211
 protein coding gene Chr2:158071381-158073160 (+)
PWK/PhJ MGP_PWKPhJ_G0025644
 protein coding gene Chr2:152405859-152407635 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025447
 protein coding gene Chr2:157001534-157003309 (+)
WSB/EiJ MGP_WSBEiJ_G0025980
 protein coding gene Chr2:158955714-158958583 (+)



Homology
more
  • Human Ortholog
    MAP1LC3A, microtubule associated protein 1 light chain 3 alpha
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MAP1LC3A, microtubule associated protein 1 light chain 3 alpha
  • Synonyms
    ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3
  • Links
    NCBI Gene ID: 84557
    neXtProt AC: NX_Q9H492
    UniProt: Q9H492

  • Chr Location
    20q11.22; chr20:34546844-34560345 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human MAP1LC3A associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    59
  • GO References
    21
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    943
  • Tissues
    105
  • cDNA Data
    136
  • Literature Summary
    47
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 66734 NCBI Gene Model | MGI Sequence Detail 1710 C57BL/6J ±  kb
transcript NM_025735 RefSeq | MGI Sequence Detail 1063 C57BL/6  
polypeptide Q91VR7 UniProt | EBI | MGI Sequence Detail 121 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010119 microtubule-associated proteins 1A/1B light chain 3A
    (term hierarchy)
  • InterPro Domains
    IPR004241 Autophagy protein Atg8 ubiquitin-like
    IPR029071 Ubiquitin-like domain superfamily
  • GlyGen
    Q91VR7 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 141
    cDNA 136
    Primer pair 4
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1913984
References
more
  • Summaries
    All 137
    Developmental Gene Expression 47
    Gene Ontology 21
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:354208 Dong MZ, et al., Protein phosphatase 4 maintains the survival of primordial follicles by regulating autophagy in oocytes. Cell Death Dis. 2024 Sep 8;15(9):658
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory