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Scgb3a1 Gene Detail
Summary
  • Symbol
    Scgb3a1
  • Name
    secretoglobin, family 3A, member 1
  • Synonyms
    1110030K16Rik, HIN-1, LuLeu2, UGRP2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915912
    NCBI Gene: 68662
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
  • Candidate for QTL
    1 QTL
Location &
Maps
more
  • Sequence Map
    Chr11:49554437-49555945 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 29.75 cM, cytoband B1.2
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    123 from dbSNP Build 142
  • Strain Annotations
    18
  • RFLP
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915912
 protein coding gene Chr11:49554422-49555945 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018235
 protein coding gene Chr11:48802787-48804295 (+)
A/J MGP_AJ_G0018203
 protein coding gene Chr11:46921109-46922617 (+)
AKR/J MGP_AKRJ_G0018173
 protein coding gene Chr11:48426539-48428047 (+)
BALB/cJ MGP_BALBcJ_G0018173
 protein coding gene Chr11:47206024-47207532 (+)
C3H/HeJ MGP_C3HHeJ_G0017986
 protein coding gene Chr11:48424623-48426131 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018624
 protein coding gene Chr11:50256309-50257817 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016276
 protein coding gene Chr11:44546796-44548299 (+)
CAST/EiJ MGP_CASTEiJ_G0017548
 protein coding gene Chr11:48388242-48389742 (+)
CBA/J MGP_CBAJ_G0017961
 protein coding gene Chr11:52592782-52594290 (+)
DBA/2J MGP_DBA2J_G0018068
 protein coding gene Chr11:46737376-46738884 (+)
FVB/NJ MGP_FVBNJ_G0018062
 protein coding gene Chr11:46353258-46354766 (+)
LP/J MGP_LPJ_G0018143
 protein coding gene Chr11:49131613-49133121 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018087
 protein coding gene Chr11:54136702-54138210 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018668
 protein coding gene Chr11:48526996-48528504 (+)
PWK/PhJ MGP_PWKPhJ_G0017326
 protein coding gene Chr11:47121082-47122649 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017121
 protein coding gene Chr11:48225720-48227219 (+)
WSB/EiJ MGP_WSBEiJ_G0017601
 protein coding gene Chr11:48171348-48172856 (+)



Homology
more
  • Human Ortholog
    SCGB3A1, secretoglobin family 3A member 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SCGB3A1, secretoglobin family 3A member 1
  • Synonyms
    HIN-1, HIN1, LU105, PnSP-2, UGRP2
  • Links
    NCBI Gene ID: 92304
    neXtProt AC: NX_Q96QR1
    UniProt: Q96QR1

  • Chr Location
    5q35.3; chr5:180590105-180591499 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 2 genetic backgrounds
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    4
  • Gene trapped
    2
  • Targeted
    4
  • Genomic Mutations
    1 involving Scgb3a1
  • Find Mice (IMSR)
    9 strains or lines available
Mice homozygous for a null allele exhibit reduced ciliated cells in the lungs.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    816
  • Tissues
    56
  • cDNA Data
    17
  • Literature Summary
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000064057 Ensembl Gene Model | MGI Sequence Detail 1509 C57BL/6J ±  kb
transcript ENSMUST00000043873 Ensembl | MGI Sequence Detail 493 Not Applicable  
polypeptide ENSMUSP00000043325 Ensembl | MGI Sequence Detail 104 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 17
    Primer pair 6

    Microarray probesets 3
References
more
  • Summaries
    All 53
    Developmental Gene Expression 11
    Gene Ontology 6
    Phenotypes 16
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory