About   Help   FAQ
Ppp1r27 Gene Detail
Summary
  • Symbol
    Ppp1r27
  • Name
    protein phosphatase 1, regulatory subunit 27
  • Synonyms
    1110033I14Rik, Dysfip1, toonin
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915951
    NCBI Gene: 68701
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:120440805-120441958 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 84.26 cM, cytoband E2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915951
 protein coding gene Chr11:120440801-120441958 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019509
 protein coding gene Chr11:125019112-125020265 (-)
A/J MGP_AJ_G0019477
 protein coding gene Chr11:119459076-119460229 (-)
AKR/J MGP_AKRJ_G0019447
 protein coding gene Chr11:123052438-123053591 (-)
BALB/cJ MGP_BALBcJ_G0019452
 protein coding gene Chr11:119814397-119815550 (-)
C3H/HeJ MGP_C3HHeJ_G0019258
 protein coding gene Chr11:123390199-123391352 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019900
 protein coding gene Chr11:128802891-128804044 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017526
 protein coding gene Chr11:116450889-116452040 (-)
CAST/EiJ MGP_CASTEiJ_G0018812
 protein coding gene Chr11:124883798-124884950 (-)
CBA/J MGP_CBAJ_G0019229
 protein coding gene Chr11:133843742-133844895 (-)
DBA/2J MGP_DBA2J_G0019341
 protein coding gene Chr11:118828383-118829536 (-)
FVB/NJ MGP_FVBNJ_G0019333
 protein coding gene Chr11:118539111-118540264 (-)
LP/J MGP_LPJ_G0019413
 protein coding gene Chr11:125324446-125325599 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019366
 protein coding gene Chr11:132680610-132681763 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019940
 protein coding gene Chr11:123741131-123742284 (-)
PWK/PhJ MGP_PWKPhJ_G0018578
 protein coding gene Chr11:120262804-120263956 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018370
 protein coding gene Chr11:123501568-123502719 (-)
WSB/EiJ MGP_WSBEiJ_G0018864
 protein coding gene Chr11:123728389-123729542 (-)



Homology
more
  • Human Ortholog
    PPP1R27, protein phosphatase 1 regulatory subunit 27
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPP1R27, protein phosphatase 1 regulatory subunit 27
  • Synonyms
    DYSFIP1
  • Links
    NCBI Gene ID: 116729
    neXtProt AC: NX_Q86WC6
    UniProt: Q86WC6

  • Chr Location
    17q25.3; chr17:81833492-81835050 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025129 Ensembl Gene Model | MGI Sequence Detail 1154 C57BL/6J ±  kb
transcript ENSMUST00000026121 Ensembl | MGI Sequence Detail 771 Not Applicable  
polypeptide ENSMUSP00000026121 Ensembl | MGI Sequence Detail 154 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 3
References
more
  • Summaries
    All 26
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory