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Atp6v1c2 Gene Detail
Summary
  • Symbol
    Atp6v1c2
  • Name
    ATPase, H+ transporting, lysosomal V1 subunit C2
  • Synonyms
    1110038G14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916025
    NCBI Gene: 68775
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:17334722-17375700 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 8.06 cM, cytoband A3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1242 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916025
 protein coding gene Chr12:17334722-17379360 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019618
 protein coding gene Chr12:14711137-14758645 (-)
A/J MGP_AJ_G0019585
 protein coding gene Chr12:14191554-14237045 (-)
AKR/J MGP_AKRJ_G0019555
 protein coding gene Chr12:14860809-14905303 (-)
BALB/cJ MGP_BALBcJ_G0019561
 protein coding gene Chr12:14436430-14480665 (-)
C3H/HeJ MGP_C3HHeJ_G0019366
 protein coding gene Chr12:14760913-14807247 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020009
 protein coding gene Chr12:15192490-15249363 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017635
 protein coding gene Chr12:13686276-13730268 (-)
CAST/EiJ MGP_CASTEiJ_G0018921
 protein coding gene Chr12:14659364-14712793 (-)
CBA/J MGP_CBAJ_G0019337
 protein coding gene Chr12:16022535-16069529 (-)
DBA/2J MGP_DBA2J_G0019450
 protein coding gene Chr12:14104952-14150863 (-)
FVB/NJ MGP_FVBNJ_G0019441
 protein coding gene Chr12:13989531-14037612 (-)
LP/J MGP_LPJ_G0019521
 protein coding gene Chr12:14827779-14876614 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019476
 protein coding gene Chr12:15890437-15937215 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020048
 protein coding gene Chr12:14543543-14592560 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0018477
 protein coding gene Chr12:14740277-14785055 (-)
WSB/EiJ MGP_WSBEiJ_G0018972
 protein coding gene Chr12:14671568-14718227 (-)



Homology
more
  • Human Ortholog
    ATP6V1C2, ATPase H+ transporting V1 subunit C2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ATP6V1C2, ATPase H+ transporting V1 subunit C2
  • Synonyms
    ATP6C2, VMA5
  • Links
    NCBI Gene ID: 245973
    neXtProt AC: NX_Q8NEY4
    UniProt: Q8NEY4

  • Chr Location
    2p25.1; chr2:10720943-10785110 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    852
  • Tissues
    114
  • cDNA Data
    62
  • Literature Summary
    8
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68775 NCBI Gene Model | MGI Sequence Detail 40979 C57BL/6J ±  kb
transcript NM_001159632 RefSeq | MGI Sequence Detail 1597 C57BL/6  
polypeptide Q99L60 UniProt | EBI | MGI Sequence Detail 427 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 63
    cDNA 62
    Primer pair 1

    Microarray probesets 2
References
more
  • Summaries
    All 33
    Developmental Gene Expression 8
    Gene Ontology 6
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:332874 Jones MR, et al., FGFR2b signalling restricts lineage-flexible alveolar progenitors during mouse lung development and converges in mature alveolar type 2 cells. Cell Mol Life Sci. 2022 Nov 29;79(12):609
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory