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Zfp467 Gene Detail
Summary
  • Symbol
    Zfp467
  • Name
    zinc finger protein 467
  • Synonyms
    1190001I08Rik, EZI, MNCb-3350
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916160
    NCBI Gene: 68910
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:48404631-48422759 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 23.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    481 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916160
 protein coding gene Chr6:48404626-48422926 (-)
129S1/SvImJ MGP_129S1SvImJ_G0030693
 protein coding gene Chr6:47364363-47383415 (-)
A/J MGP_AJ_G0030664
 protein coding gene Chr6:45218193-45236230 (-)
AKR/J MGP_AKRJ_G0030589
 protein coding gene Chr6:46811815-46831151 (-)
BALB/cJ MGP_BALBcJ_G0030674
 protein coding gene Chr6:45553217-45571062 (-)
C3H/HeJ MGP_C3HHeJ_G0030387
 protein coding gene Chr6:46813382-46832452 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031129
 protein coding gene Chr6:48486901-48504559 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028335
 protein coding gene Chr6:42853761-42871783 (-)
CAST/EiJ MGP_CASTEiJ_G0029791
 protein coding gene Chr6:46533780-46552869 (-)
CBA/J MGP_CBAJ_G0030362
 protein coding gene Chr6:50499521-50518630 (-)
DBA/2J MGP_DBA2J_G0030511
 protein coding gene Chr6:45137364-45155330 (-)
FVB/NJ MGP_FVBNJ_G0030463
 protein coding gene Chr6:44766056-44785199 (-)
LP/J MGP_LPJ_G0030596
 protein coding gene Chr6:47340798-47359106 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030497
 protein coding gene Chr6:53315960-53338967 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031158
 protein coding gene Chr6:46667389-46689438 (-)
PWK/PhJ MGP_PWKPhJ_G0029503
 protein coding gene Chr6:44665796-44684449 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029339
 protein coding gene Chr6:46023398-46041551 (-)
WSB/EiJ MGP_WSBEiJ_G0029868
 protein coding gene Chr6:46669442-46688868 (-)



Homology
more
  • Human Ortholog
    ZNF467, zinc finger protein 467
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF467, zinc finger protein 467
  • Synonyms
    EZI, Zfp467
  • Links
    NCBI Gene ID: 168544
    neXtProt AC: NX_Q7Z7K2
    UniProt: Q7Z7K2

  • Chr Location
    7q36.1; chr7:149764182-149776530 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    28 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele are small with less body fat, exhibit higher trabecular bone and cortical bone area, reduced marrow adipocyte numbers, improved glucose tolerance, and are resistant to ovariectomy-induced adiposity and high-fat diet-induced adiposity and weight gain.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    771
  • Tissues
    49
  • cDNA Data
    52
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000068551 Ensembl Gene Model | MGI Sequence Detail 18129 C57BL/6J ±  kb
    transcript ENSMUST00000114560 Ensembl | MGI Sequence Detail 3266 Not Applicable  
    polypeptide ENSMUSP00000110207 Ensembl | MGI Sequence Detail 594 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 52
      cDNA 52

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1930785, MGI:2141403, MGI:2141610
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 3
      Gene Ontology 3
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory