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Zfas1 Gene Detail
Summary
  • Symbol
    Zfas1
  • Name
    zinc finger, NFX1-type containing 1, antisense RNA 1
  • Synonyms
    1500012F01Rik, Zfos1
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1916199
    NCBI Gene: 68949
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:166904854-166907782 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 87.22 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    144 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916199
lncRNA gene Chr2:166904854-166907783 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026908
protein coding gene Chr2:172762489-172765211 (+)
A/J MGP_AJ_G0026875
protein coding gene Chr2:165666915-165669843 (+)
AKR/J MGP_AKRJ_G0026846
protein coding gene Chr2:170597885-170600747 (+)
BALB/cJ MGP_BALBcJ_G0026884
protein coding gene Chr2:166015839-166019016 (+)
C3H/HeJ MGP_C3HHeJ_G0026626
protein coding gene Chr2:170966071-170970195 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027331
protein coding gene Chr2:177780901-177785879 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024702
protein coding gene Chr2:158994733-158997752 (+)
CAST/EiJ MGP_CASTEiJ_G0026084
protein coding gene Chr2:171424638-171427361 (+)
CBA/J MGP_CBAJ_G0026603
protein coding gene Chr2:184303199-184307893 (+)
DBA/2J MGP_DBA2J_G0026741
protein coding gene Chr2:164787822-164790987 (+)
FVB/NJ MGP_FVBNJ_G0026707
protein coding gene Chr2:163293498-163296552 (+)
LP/J MGP_LPJ_G0026842
protein coding gene Chr2:172786325-172789047 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026726
protein coding gene Chr2:187706094-187709816 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027388
protein coding gene Chr2:170506557-170509485 (+)
PWK/PhJ MGP_PWKPhJ_G0025821
protein coding gene Chr2:164440768-164443488 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025622
protein coding gene Chr2:169455227-169457925 (+)
WSB/EiJ MGP_WSBEiJ_G0026157
protein coding gene Chr2:171408616-171411338 (+)



Homology
more
  • Human Ortholog
    ZFAS1, ZNFX1 antisense RNA 1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZFAS1, ZNFX1 antisense RNA 1
  • Synonyms
    C20orf199, HSUP1, HSUP2, NCRNA00275, ZNFX1-AS1
  • Links
    NCBI Gene ID: 441951

  • Chr Location
    20q13.13; chr20:49278178-49299600 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68949 NCBI Gene Model | MGI Sequence Detail 2929 C57BL/6J ±  kb
    transcript NR_138563 RefSeq | MGI Sequence Detail 754 C57BL/6  
    polypeptide Q3V494 UniProt | EBI | MGI Sequence Detail 79 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    Molecular
    Reagents
    less
    • All nucleic 39
      cDNA 39

      Microarray probesets 3
    References
    more
    • Summaries
      All 22
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:294533 Jiao L, et al., lncRNA-ZFAS1 induces mitochondria-mediated apoptosis by causing cytosolic Ca(2+) overload in myocardial infarction mice model. Cell Death Dis. 2019 Dec 9;10(12):942

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    11/19/2024
    MGI 6.24
    The Jackson Laboratory