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Chmp2a Gene Detail
Summary
  • Symbol
    Chmp2a
  • Name
    charged multivesicular body protein 2A
  • Synonyms
    1500016L11Rik, chromatin modifying protein 2A
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916203
    NCBI Gene: 68953
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:12765933-12768704 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 7.73 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    88 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916203
 protein coding gene Chr7:12765933-12768734 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031663
 protein coding gene Chr7:10440654-10443387 (-)
A/J MGP_AJ_G0031636
 protein coding gene Chr7:10280308-10283083 (-)
AKR/J MGP_AKRJ_G0031559
 protein coding gene Chr7:10507954-10512149 (-)
BALB/cJ MGP_BALBcJ_G0031641
 protein coding gene Chr7:10394814-10397586 (-)
C3H/HeJ MGP_C3HHeJ_G0031363
 protein coding gene Chr7:10614293-10617080 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032105
 protein coding gene Chr7:10970357-10973170 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029199
 protein coding gene Chr7:11878204-11880995 (-)
CAST/EiJ MGP_CASTEiJ_G0030721
 protein coding gene Chr7:8169099-8173962 (-)
CBA/J MGP_CBAJ_G0031320
 protein coding gene Chr7:11190111-11192882 (-)
DBA/2J MGP_DBA2J_G0031478
 protein coding gene Chr7:10162809-10165578 (-)
FVB/NJ MGP_FVBNJ_G0031434
 protein coding gene Chr7:10160589-10163298 (-)
LP/J MGP_LPJ_G0031565
 protein coding gene Chr7:10525178-10527960 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0031469
 protein coding gene Chr7:11275729-11278502 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032135
 protein coding gene Chr7:10295565-10300665 (-)
PWK/PhJ MGP_PWKPhJ_G0030449
 protein coding gene Chr7:8646780-8649527 (-)
SPRET/EiJ MGP_SPRETEiJ_G0030275
 protein coding gene Chr7:6407575-6410392 (-)
WSB/EiJ MGP_WSBEiJ_G0030816
 protein coding gene Chr7:10326409-10329182 (-)



Homology
more
  • Human Ortholog
    CHMP2A, charged multivesicular body protein 2A
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHMP2A, charged multivesicular body protein 2A
  • Synonyms
    BC-2, BC2, CHMP2, VPS2, VPS2A
  • Links
    NCBI Gene ID: 27243
    neXtProt AC: NX_O43633
    UniProt: O43633

  • Chr Location
    19q13.43; chr19:58551452-58555105 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    85
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    860
  • Tissues
    49
  • cDNA Data
    100
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68953 NCBI Gene Model | MGI Sequence Detail 2772 C57BL/6J ±  kb
transcript NM_001360730 RefSeq | MGI Sequence Detail 1060 C57BL/6  
polypeptide Q9DB34 UniProt | EBI | MGI Sequence Detail 222 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 102
    cDNA 100
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 37
    Developmental Gene Expression 3
    Gene Ontology 9
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:339600 Hermosilla Aguayo V, et al., ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory