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Snrpa1 Gene Detail
Summary
  • Symbol
    Snrpa1
  • Name
    small nuclear ribonucleoprotein polypeptide A'
  • Synonyms
    1500015N06Rik, U2 snRNP-A'
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916231
    NCBI Gene: 68981
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:65710084-65724335 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 35.47 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    483 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916231
 protein coding gene Chr7:65708751-65724335 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032347
 protein coding gene Chr7:67278707-67294349 (+)
A/J MGP_AJ_G0032326
 protein coding gene Chr7:65902122-65917741 (+)
AKR/J MGP_AKRJ_G0032262
 protein coding gene Chr7:67302074-67317521 (+)
BALB/cJ MGP_BALBcJ_G0032338
 protein coding gene Chr7:65632663-65648222 (+)
C3H/HeJ MGP_C3HHeJ_G0032051
 protein coding gene Chr7:67969633-67986507 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032831
 protein coding gene Chr7:70179493-70196007 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029838
 protein coding gene Chr7:68801182-68816773 (+)
CAST/EiJ MGP_CASTEiJ_G0031380
 protein coding gene Chr7:58646297-58663288 (+)
CBA/J MGP_CBAJ_G0032017
 protein coding gene Chr7:72359489-72377160 (+)
DBA/2J MGP_DBA2J_G0032173
 protein coding gene Chr7:64616189-64632796 (+)
FVB/NJ MGP_FVBNJ_G0032127
 protein coding gene Chr7:64749259-64766291 (+)
LP/J MGP_LPJ_G0032253
 protein coding gene Chr7:68493825-68509423 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032164
 protein coding gene Chr7:72612543-72628155 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032848
 protein coding gene Chr7:66651120-66666647 (+)
PWK/PhJ MGP_PWKPhJ_G0031100
 protein coding gene Chr7:57650674-57667284 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030941
 protein coding gene Chr7:53704940-53727689 (+)
WSB/EiJ MGP_WSBEiJ_G0031498
 protein coding gene Chr7:66981358-66997384 (+)



Homology
more
  • Human Ortholog
    SNRPA1, small nuclear ribonucleoprotein polypeptide A'
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SNRPA1, small nuclear ribonucleoprotein polypeptide A'
  • Synonyms
    Lea1, U2A'
  • Links
    NCBI Gene ID: 6627
    neXtProt AC: NX_P09661
    UniProt: P09661

  • Chr Location
    15q26.3; chr15:101281510-101295282 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SNRPA1 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    924
  • Tissues
    92
  • cDNA Data
    79
  • Literature Summary
    5
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68981 NCBI Gene Model | MGI Sequence Detail 14252 C57BL/6J ±  kb
transcript NM_021336 RefSeq | MGI Sequence Detail 1250 C57BL/6  
polypeptide P57784 UniProt | EBI | MGI Sequence Detail 255 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000015340 U2 small nuclear ribonucleoprotein A'
    (term hierarchy)
  • InterPro Domains
    IPR001611 Leucine-rich repeat
    IPR032675 Leucine-rich repeat domain superfamily
    IPR003603 U2A'/phosphoprotein 32 family A, C-terminal
  • GlyGen
    P57784 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 82
    cDNA 80
    Primer pair 2

    Microarray probesets 5
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
  • Latest
    J:299860 Jin L, et al., STRAP regulates alternative splicing fidelity during lineage commitment of mouse embryonic stem cells. Nat Commun. 2020 Nov 23;11(1):5941
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory