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Chaserr Gene Detail
Summary
  • Symbol
    Chaserr
  • Name
    CHD2 adjacent suppressive regulatory RNA
  • Synonyms
    1810026B05Rik
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1916420
    NCBI Gene: 69170
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:73189549-73208143 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 42.03 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    429 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916420
 lncRNA gene Chr7:73189546-73208143 (-)
129S1/SvImJ MGP_129S1SvImJ_G0015675
 unclassified non-coding RNA gene Chr7:75102674-75121902 (-)
A/J MGP_AJ_G0015654
 unclassified non-coding RNA gene Chr7:73417546-73436718 (-)
AKR/J MGP_AKRJ_G0015617
 unclassified non-coding RNA gene Chr7:74950374-74969540 (-)
BALB/cJ MGP_BALBcJ_G0015615
 unclassified non-coding RNA gene Chr7:73167812-73187616 (-)
C3H/HeJ MGP_C3HHeJ_G0015437
 unclassified non-coding RNA gene Chr7:75721284-75740453 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016069
 unclassified non-coding RNA gene Chr7:78208516-78228879 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0013799
 unclassified non-coding RNA gene Chr7:76048998-76068161 (-)
CAST/EiJ MGP_CASTEiJ_G0014992
 unclassified non-coding RNA gene Chr7:66537556-66557930 (-)
CBA/J MGP_CBAJ_G0015418
 unclassified non-coding RNA gene Chr7:80748131-80767286 (-)
DBA/2J MGP_DBA2J_G0015513
 unclassified non-coding RNA gene Chr7:72078431-72099958 (-)
FVB/NJ MGP_FVBNJ_G0015520
 unclassified non-coding RNA gene Chr7:72132597-72152526 (-)
LP/J MGP_LPJ_G0015593
 unclassified non-coding RNA gene Chr7:76329535-76349318 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015542
 unclassified non-coding RNA gene Chr7:80883742-80908238 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016111
 unclassified non-coding RNA gene Chr7:74425166-74444356 (-)
PWK/PhJ MGP_PWKPhJ_G0014774
 unclassified non-coding RNA gene Chr7:65239995-65259540 (-)
SPRET/EiJ MGP_SPRETEiJ_G0014563
 unclassified non-coding RNA gene Chr7:61492315-61514800 (-)
WSB/EiJ MGP_WSBEiJ_G0015097
 unclassified non-coding RNA gene Chr7:74766938-74786607 (-)



Homology
more
  • Human Ortholog
    CHASERR, CHD2 adjacent suppressive regulatory RNA
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CHASERR, CHD2 adjacent suppressive regulatory RNA
  • Synonyms
    LINC01578, NEDFSAB
  • Links
    NCBI Gene ID: 100507217

  • Chr Location
    chr15:92819305-92899701 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 2 alleles in 1 genetic background
    3 phenotypes from multigenic genotypes
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit preweaning lethality. Mice heterozygous for the allele exhibit partial postnatal lethality, reduced body weight, reduced fat mass, malocclusion, and kyphosis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    7
  • cDNA Data
    4
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      38
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000101970 Ensembl Gene Model | MGI Sequence Detail 18595 C57BL/6J ±  kb
    transcript ENSMUST00000184587 Ensembl | MGI Sequence Detail 5140 Not Applicable  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 4
      Primer pair 1

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:6430454
    References
    more
    • Summaries
      All 22
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 10
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:281371 Rom A, et al., Regulation of CHD2 expression by the Chaserr long noncoding RNA gene is essential for viability. Nat Commun. 2019 Nov 8;10(1):5092
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    12/17/2024
    MGI 6.24     		The Jackson Laboratory