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Smim23 Gene Detail
Summary
  • Symbol
    Smim23
  • Name
    small integral membrane protein 23
  • Synonyms
    1700008A04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916601
    NCBI Gene: 69351
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:32770376-32774594 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 19.11 cM, cytoband A5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    240 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916601
 protein coding gene Chr11:32768529-32774605 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018139
 protein coding gene Chr11:31072203-31079642 (-)
A/J MGP_AJ_G0018112
 protein coding gene Chr11:29893047-29898692 (-)
AKR/J MGP_AKRJ_G0018076
 protein coding gene Chr11:30830674-30836612 (-)
BALB/cJ MGP_BALBcJ_G0018081
 protein coding gene Chr11:30074112-30080163 (-)
C3H/HeJ MGP_C3HHeJ_G0017894
 protein coding gene Chr11:30775563-30782233 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018535
 protein coding gene Chr11:32087643-32093987 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016190
 protein coding gene Chr11:28409630-28416616 (-)
CAST/EiJ MGP_CASTEiJ_G0017458
 protein coding gene Chr11:30831057-30837506 (-)
CBA/J MGP_CBAJ_G0017867
 protein coding gene Chr11:33608058-33615947 (-)
DBA/2J MGP_DBA2J_G0017977
 protein coding gene Chr11:29675573-29680922 (-)
FVB/NJ MGP_FVBNJ_G0017971
 protein coding gene Chr11:29506737-29513143 (-)
LP/J MGP_LPJ_G0018049
 protein coding gene Chr11:31332395-31339364 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017995
 protein coding gene Chr11:34579264-34585773 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018574
 protein coding gene Chr11:30973785-30980312 (-)
PWK/PhJ MGP_PWKPhJ_G0017239
 protein coding gene Chr11:29840106-29846111 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017031
 protein coding gene Chr11:30670501-30677582 (-)
WSB/EiJ MGP_WSBEiJ_G0017507
 protein coding gene Chr11:30602357-30607882 (-)



Homology
more
  • Human Ortholog
    SMIM23, small integral membrane protein 23
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SMIM23, small integral membrane protein 23
  • Synonyms
    C5orf50
  • Links
    NCBI Gene ID: 644994
    neXtProt AC: NX_A6NLE4
    UniProt: A6NLE4

  • Chr Location
    5q35.1; chr5:171772637-171796126 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Male mice homozygous for a mutation are viable and show normal fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69351 NCBI Gene Model | MGI Sequence Detail 4219 C57BL/6J ±  kb
    transcript NM_027050 RefSeq | MGI Sequence Detail 606 C57BL/6  
    polypeptide Q9DAL0 UniProt | EBI | MGI Sequence Detail 136 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 2
      cDNA 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 28
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory