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Wdr20 Gene Detail
Summary
  • Symbol
    Wdr20
  • Name
    WD repeat domain 20
  • Synonyms
    2310040A13Rik, Wdr20a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916891
    NCBI Gene: 69641
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:110704378-110770672 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 60.78 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1397 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916891
 protein coding gene Chr12:110701459-110770709 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020121
 protein coding gene Chr12:113058477-113139462 (+)
A/J MGP_AJ_G0020075
 protein coding gene Chr12:108725974-108793744 (+)
AKR/J MGP_AKRJ_G0020051
 protein coding gene Chr12:111854039-111927480 (+)
BALB/cJ MGP_BALBcJ_G0020061
 protein coding gene Chr12:109151347-109219568 (+)
C3H/HeJ MGP_C3HHeJ_G0019863
 protein coding gene Chr12:112306916-112378753 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020506
 protein coding gene Chr12:116532981-116669799 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018118
 protein coding gene Chr12:105182163-105248722 (+)
CAST/EiJ MGP_CASTEiJ_G0019404
 protein coding gene Chr12:107188947-107268796 (+)
CBA/J MGP_CBAJ_G0019830
 protein coding gene Chr12:121065465-121135799 (+)
DBA/2J MGP_DBA2J_G0019947
 protein coding gene Chr12:108213402-108282103 (+)
FVB/NJ MGP_FVBNJ_G0019932
 protein coding gene Chr12:107013882-107082086 (+)
LP/J MGP_LPJ_G0020022
 protein coding gene Chr12:112895839-112970372 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0019970
 protein coding gene Chr12:124178726-124273766 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020535
 protein coding gene Chr12:111333994-111412367 (+)
PWK/PhJ MGP_PWKPhJ_G0019164
 protein coding gene Chr12:102845032-102912977 (+)
SPRET/EiJ MGP_SPRETEiJ_G0018968
 protein coding gene Chr12:105524222-105593475 (+)
WSB/EiJ MGP_WSBEiJ_G0019462
 protein coding gene Chr12:112255764-112347718 (+)



Homology
more
  • Human Ortholog
    WDR20, WD repeat domain 20
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR20, WD repeat domain 20
  • Synonyms
    Bun107, DMR
  • Links
    NCBI Gene ID: 91833
    neXtProt AC: NX_Q8TBZ3
    UniProt: Q8TBZ3

  • Chr Location
    14q32.31; chr14:102139423-102224847 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037957 Ensembl Gene Model | MGI Sequence Detail 66295 C57BL/6J ±  kb
transcript ENSMUST00000095410 Ensembl | MGI Sequence Detail 2384 Not Applicable  
polypeptide ENSMUSP00000093059 Ensembl | MGI Sequence Detail 569 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR001680 WD40 repeat
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
    IPR051362 WD repeat creC family regulators
  • GlyGen
    Q3UWE6 3 sites, 3 N-linked glycans (3 sites)
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 7
Other
Accession IDs
less
MGI:2144859
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 7
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:205485 Yu C, et al., CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins. Science. 2013 Dec 20;342(6165):1518-21
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory