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Txndc15 Gene Detail
Summary
  • Symbol
    Txndc15
  • Name
    thioredoxin domain containing 15
  • Synonyms
    2310047H23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916922
    NCBI Gene: 69672
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:55862463-55874040 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 30.06 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    448 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916922
 protein coding gene Chr13:55862463-55874040 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020609
 protein coding gene Chr13:55217341-55228912 (+)
A/J MGP_AJ_G0020563
 protein coding gene Chr13:53177701-53189375 (+)
AKR/J MGP_AKRJ_G0020541
 protein coding gene Chr13:54756415-54768419 (+)
BALB/cJ MGP_BALBcJ_G0020559
 protein coding gene Chr13:53406844-53418412 (+)
C3H/HeJ MGP_C3HHeJ_G0020358
 protein coding gene Chr13:54555938-54568587 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020993
 protein coding gene Chr13:56874987-56886525 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018575
 protein coding gene Chr13:51109223-51122469 (+)
CAST/EiJ MGP_CASTEiJ_G0019872
 protein coding gene Chr13:54669125-54681320 (+)
CBA/J MGP_CBAJ_G0020318
 protein coding gene Chr13:59071764-59083721 (+)
DBA/2J MGP_DBA2J_G0020441
 protein coding gene Chr13:52724187-52735779 (+)
FVB/NJ MGP_FVBNJ_G0020420
 protein coding gene Chr13:52192466-52204155 (+)
LP/J MGP_LPJ_G0020517
 protein coding gene Chr13:55467862-55480825 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020449
 protein coding gene Chr13:58523506-58535007 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021036
 protein coding gene Chr13:54329685-54342131 (+)
PWK/PhJ MGP_PWKPhJ_G0019628
 protein coding gene Chr13:52751756-52764074 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019455
 protein coding gene Chr13:53244138-53259635 (+)
WSB/EiJ MGP_WSBEiJ_G0019934
 protein coding gene Chr13:54698487-54710050 (+)



Homology
more
  • Human Ortholog
    TXNDC15, thioredoxin domain containing 15
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TXNDC15, thioredoxin domain containing 15
  • Synonyms
    BUG, C5orf14, MKS14, UNQ335
  • Links
    NCBI Gene ID: 79770
    neXtProt AC: NX_Q96J42
    UniProt: Q96J42

  • Chr Location
    5q31.1; chr5:134873770-134901635 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TXNDC15 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69672 NCBI Gene Model | MGI Sequence Detail 11578 C57BL/6J ±  kb
transcript NM_175150 RefSeq | MGI Sequence Detail 1554 Not Specified  
polypeptide Q6P6J9 UniProt | EBI | MGI Sequence Detail 344 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 5
Other
Accession IDs
less
MGI:2145309
References
more
  • Summaries
    All 32
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:262140 Breslow DK, et al., A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies. Nat Genet. 2018 Mar;50(3):460-471
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory