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Paox Gene Detail
Summary
  • Symbol
    Paox
  • Name
    polyamine oxidase (exo-N4-amino)
  • Synonyms
    2410012F02Rik, Pao
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916983
    NCBI Gene: 212503
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:139693182-139714249 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 85.14 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    676 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916983
 protein coding gene Chr7:139693182-139717137 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033165
 protein coding gene Chr7:145216238-145227198 (+)
A/J MGP_AJ_G0033147
 protein coding gene Chr7:141066475-141086907 (+)
AKR/J MGP_AKRJ_G0033079
 protein coding gene Chr7:144923921-144933262 (+)
BALB/cJ MGP_BALBcJ_G0033148
 protein coding gene Chr7:140807959-140817945 (+)
C3H/HeJ MGP_C3HHeJ_G0032862
 protein coding gene Chr7:144724913-144733341 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033659
 protein coding gene Chr7:150545514-150554789 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030632
 protein coding gene Chr7:142196887-142205338 (+)
CAST/EiJ MGP_CASTEiJ_G0032192
 protein coding gene Chr7:137024587-137038512 (+)
CBA/J MGP_CBAJ_G0032835
 protein coding gene Chr7:155620901-155632715 (+)
DBA/2J MGP_DBA2J_G0032987
 protein coding gene Chr7:139038119-139047316 (+)
FVB/NJ MGP_FVBNJ_G0032940
 protein coding gene Chr7:138932567-138942864 (+)
LP/J MGP_LPJ_G0033081
 protein coding gene Chr7:146754401-146763324 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032972
 protein coding gene Chr7:156277299-156300116 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033679
 protein coding gene Chr7:143913947-143935711 (+)
PWK/PhJ MGP_PWKPhJ_G0031898
 protein coding gene Chr7:132221838-132230488 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031743
 protein coding gene Chr7:130754366-130762739 (+)
WSB/EiJ MGP_WSBEiJ_G0032303
 protein coding gene Chr7:144814213-144824364 (+)



Homology
more
  • Human Ortholog
    PAOX, polyamine oxidase
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PAOX, polyamine oxidase
  • Synonyms
    PAO
  • Links
    NCBI Gene ID: 196743
    neXtProt AC: NX_Q6QHF9
    UniProt: Q6QHF9

  • Chr Location
    10q26.3; chr10:133379261-133391694 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human PAOX associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    34
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    784
  • Tissues
    56
  • cDNA Data
    27
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 212503 NCBI Gene Model | MGI Sequence Detail 21068 C57BL/6J ±  kb
    transcript NM_153783 RefSeq | MGI Sequence Detail 1737 C57BL/6  
    polypeptide Q8C0L6 UniProt | EBI | MGI Sequence Detail 504 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 31
      cDNA 29
      Primer pair 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2138158
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 5
      Gene Ontology 8
      Phenotypes 11
    • Earliest
      J:65007 Cattanach BM, et al., Two imprinted gene mutations: three phenotypes. Hum Mol Genet. 2000 Sep 22;9(15):2263-73
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory