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Cox11 Gene Detail
Summary
  • Symbol
    Cox11
  • Name
    cytochrome c oxidase assembly protein 11, copper chaperone
  • Synonyms
    2010004I09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917052
    NCBI Gene: 69802
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:90528999-90535757 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 55.45 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    302 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917052
 protein coding gene Chr11:90528999-90536803 (+)
129S1/SvImJ MGP_129S1SvImJ_G0018940
 protein coding gene Chr11:92481638-92489487 (+)
A/J MGP_AJ_G0018908
 protein coding gene Chr11:88862023-88869864 (+)
AKR/J MGP_AKRJ_G0018878
 protein coding gene Chr11:91595835-91602457 (+)
BALB/cJ MGP_BALBcJ_G0018881
 protein coding gene Chr11:89302452-89309475 (+)
C3H/HeJ MGP_C3HHeJ_G0018695
 protein coding gene Chr11:91612046-91620600 (+)
C57BL/6NJ MGP_C57BL6NJ_G0019333
 protein coding gene Chr11:95385837-95392624 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016964
 protein coding gene Chr11:85878710-85886046 (+)
CAST/EiJ MGP_CASTEiJ_G0018250
 protein coding gene Chr11:92348807-92356466 (+)
CBA/J MGP_CBAJ_G0018666
 protein coding gene Chr11:99334940-99343461 (+)
DBA/2J MGP_DBA2J_G0018774
 protein coding gene Chr11:88400404-88407035 (+)
FVB/NJ MGP_FVBNJ_G0018763
 protein coding gene Chr11:87921225-87927810 (+)
LP/J MGP_LPJ_G0018844
 protein coding gene Chr11:93000797-93010817 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0018790
 protein coding gene Chr11:99214239-99220884 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0019373
 protein coding gene Chr11:91841291-91848835 (+)
PWK/PhJ MGP_PWKPhJ_G0018020
 protein coding gene Chr11:89302348-89309202 (+)
SPRET/EiJ MGP_SPRETEiJ_G0017810
 protein coding gene Chr11:91400219-91406828 (+)
WSB/EiJ MGP_WSBEiJ_G0018299
 protein coding gene Chr11:91702688-91709397 (+)



Homology
more
  • Human Ortholog
    COX11, cytochrome c oxidase copper chaperone COX11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COX11, cytochrome c oxidase copper chaperone COX11
  • Synonyms
    COX11P, MC4DN23
  • Links
    NCBI Gene ID: 1353
    neXtProt AC: NX_Q9Y6N1
    UniProt: Q9Y6N1

  • Chr Location
    17q22; chr17:54951902-54968785 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human COX11 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    49
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000020544 Ensembl Gene Model | MGI Sequence Detail 6759 C57BL/6J ±  kb
transcript ENSMUST00000020851 Ensembl | MGI Sequence Detail 1224 Not Applicable  
polypeptide ENSMUSP00000020851 Ensembl | MGI Sequence Detail 275 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000005770 cytochrome c oxidase assembly protein COX11, mitochondrial
    (term hierarchy)
  • InterPro Domains
    IPR007533 Cytochrome c oxidase assembly protein CtaG/Cox11
    IPR023471 Cytochrome c oxidase assembly protein CtaG/Cox11, domain superfamily
Molecular
Reagents
less
  • All nucleic 50
    cDNA 49
    Primer pair 1

    Microarray probesets 5
References
more
  • Summaries
    All 41
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 7
    Phenotypes 13
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:316661 Barallobre MJ, et al., DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease. Cell Death Dis. 2014 Jun 12;5:e1289
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory