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Secisbp2l Gene Detail
Summary
  • Symbol
    Secisbp2l
  • Name
    SECIS binding protein 2-like
  • Synonyms
    3110001I20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917604
    NCBI Gene: 70354
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:125578906-125624790 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 61.76 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1024 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917604
 protein coding gene Chr2:125578906-125624790 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026433
 protein coding gene Chr2:128940182-128989970 (-)
A/J MGP_AJ_G0026396
 protein coding gene Chr2:123687444-123734197 (-)
AKR/J MGP_AKRJ_G0026372
 protein coding gene Chr2:127219392-127267556 (-)
BALB/cJ MGP_BALBcJ_G0026408
 protein coding gene Chr2:123978272-124024016 (-)
C3H/HeJ MGP_C3HHeJ_G0026152
 protein coding gene Chr2:127707578-127754703 (-)
C57BL/6NJ MGP_C57BL6NJ_G0026854
 protein coding gene Chr2:133042497-133095653 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024231
 protein coding gene Chr2:118467841-118516463 (-)
CAST/EiJ MGP_CASTEiJ_G0025613
 protein coding gene Chr2:127959067-128008400 (-)
CBA/J MGP_CBAJ_G0026132
 protein coding gene Chr2:137864875-137917713 (-)
DBA/2J MGP_DBA2J_G0026266
 protein coding gene Chr2:123103089-123148764 (-)
FVB/NJ MGP_FVBNJ_G0026230
 protein coding gene Chr2:121790222-121837562 (-)
LP/J MGP_LPJ_G0026371
 protein coding gene Chr2:129168792-129216009 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026250
 protein coding gene Chr2:141986071-142035609 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026909
 protein coding gene Chr2:127257873-127304160 (-)
PWK/PhJ MGP_PWKPhJ_G0025349
 protein coding gene Chr2:122643543-122689265 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025151
 protein coding gene Chr2:126337378-126389417 (-)
WSB/EiJ MGP_WSBEiJ_G0025687
 protein coding gene Chr2:128164532-128212474 (-)



Homology
more
  • Human Ortholog
    SECISBP2L, SECIS binding protein 2 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SECISBP2L, SECIS binding protein 2 like
  • Synonyms
    SBP2L, SLAN
  • Links
    NCBI Gene ID: 9728
    neXtProt AC: NX_Q93073
    UniProt: Q93073

  • Chr Location
    15q21.1; chr15:48988476-49046447 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with loss of expression in oligodendrocytes show impaired differentiation of oligodendrocytes with decreased T3 and increased T4 levels.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    119
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 70354 NCBI Gene Model | MGI Sequence Detail 45885 C57BL/6J ±  kb
    transcript NM_177608 RefSeq | MGI Sequence Detail 6797 C57BL/6  
    polypeptide Q6A098 UniProt | EBI | MGI Sequence Detail 1086 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      7 Sequences
    • Protein Ontology
      PR:000014602 selenocysteine insertion sequence-binding protein 2-like
      (term hierarchy)
    • InterPro Domains
      IPR029064 Ribosomal protein eL30-like superfamily
      IPR004038 Ribosomal protein eL8/eL30/eS12/Gadd45
      IPR040051 Selenocysteine insertion sequence-binding protein 2
    Molecular
    Reagents
    less
    • All nucleic 119
      cDNA 119

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2138988
    References
    more
    • Summaries
      All 33
      Developmental Gene Expression 1
      Gene Ontology 2
      Phenotypes 10
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory