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Steap1 Gene Detail
Summary
  • Symbol
    Steap1
  • Name
    six transmembrane epithelial antigen of the prostate 1
  • Synonyms
    2410007B19Rik, Prss24
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917608
    NCBI Gene: 70358
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:5786322-5799317 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 3.20 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    570 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917608
 protein coding gene Chr5:5786317-5799326 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029276
 protein coding gene Chr5:2643554-2654286 (-)
A/J MGP_AJ_G0029239
 protein coding gene Chr5:2540897-2554092 (-)
AKR/J MGP_AKRJ_G0029189
 protein coding gene Chr5:2590755-2605059 (-)
BALB/cJ MGP_BALBcJ_G0029257
 protein coding gene Chr5:2757092-2768319 (-)
C3H/HeJ MGP_C3HHeJ_G0028977
 protein coding gene Chr5:2809613-2822266 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029707
 protein coding gene Chr5:3030471-3042834 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026950
 protein coding gene Chr5:2605605-2618540 (-)
CAST/EiJ MGP_CASTEiJ_G0028390
 protein coding gene Chr5:2743815-2758102 (-)
CBA/J MGP_CBAJ_G0028938
 protein coding gene Chr5:3030434-3043996 (-)
DBA/2J MGP_DBA2J_G0029091
 protein coding gene Chr5:2692288-2703698 (-)
FVB/NJ MGP_FVBNJ_G0029052
 protein coding gene Chr5:2535279-2548570 (-)
LP/J MGP_LPJ_G0029180
 protein coding gene Chr5:2743975-2760204 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029079
 protein coding gene Chr5:2959353-2972921 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029738
 protein coding gene Chr5:2649433-2663226 (-)
PWK/PhJ MGP_PWKPhJ_G0028112
 protein coding gene Chr5:2617315-2629916 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027945
 protein coding gene Chr5:2931000-2942797 (-)
WSB/EiJ MGP_WSBEiJ_G0028470
 protein coding gene Chr5:2685899-2699235 (-)



Homology
more
  • Human Ortholog
    STEAP1, STEAP family member 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STEAP1, STEAP family member 1
  • Synonyms
    PRSS24, STEAP
  • Links
    NCBI Gene ID: 26872
    neXtProt AC: NX_Q9UHE8
    UniProt: Q9UHE8

  • Chr Location
    7q21.13; chr7:90154456-90164829 (+)  GRCh38
  • Human Ortholog
    STEAP1B, STEAP family member 1B
  • Links
    NCBI Gene ID: 256227
    neXtProt AC: NX_Q6NZ63
    UniProt: Q6NZ63

  • Chr Location
    7p15.3; chr7:22419444-22727613 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    751
  • Tissues
    30
  • cDNA Data
    8
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70358 NCBI Gene Model | MGI Sequence Detail 12996 C57BL/6J ±  kb
transcript NM_027399 RefSeq | MGI Sequence Detail 1216 C57BL/6  
polypeptide Q9CWR7 UniProt | EBI | MGI Sequence Detail 339 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 8
    Primer pair 2

    Microarray probesets 4
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:199301 Lavado A, et al., Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory