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Ipo5 Gene Detail
Summary
  • Symbol
    Ipo5
  • Name
    importin 5
  • Synonyms
    1110011C18Rik, 5730478E03Rik, IMB3, importin beta 3, Kpnb3, RanBP5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917822
    NCBI Gene: 70572
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr14:121148636-121185411 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 14, 64.81 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    991 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917822
 protein coding gene Chr14:121134271-121185451 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021659
 protein coding gene Chr14:118651106-118690163 (+)
A/J MGP_AJ_G0021619
 protein coding gene Chr14:114107716-114144679 (+)
AKR/J MGP_AKRJ_G0021595
 protein coding gene Chr14:117793036-117830995 (+)
BALB/cJ MGP_BALBcJ_G0021625
 protein coding gene Chr14:114644503-114682354 (+)
C3H/HeJ MGP_C3HHeJ_G0021403
 protein coding gene Chr14:117687101-117724245 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022065
 protein coding gene Chr14:123240013-123279444 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019603
 protein coding gene Chr14:110011036-110049187 (+)
CAST/EiJ MGP_CASTEiJ_G0020918
 protein coding gene Chr14:115559106-115600617 (+)
CBA/J MGP_CBAJ_G0021371
 protein coding gene Chr14:127942075-127978912 (+)
DBA/2J MGP_DBA2J_G0021494
 protein coding gene Chr14:113984002-114021191 (+)
FVB/NJ MGP_FVBNJ_G0021472
 protein coding gene Chr14:112300147-112337131 (+)
LP/J MGP_LPJ_G0021562
 protein coding gene Chr14:119636184-119673637 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021499
 protein coding gene Chr14:132973580-133010825 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022088
 protein coding gene Chr14:117339653-117376927 (+)
PWK/PhJ MGP_PWKPhJ_G0020662
 protein coding gene Chr14:111023840-111061956 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020500
 protein coding gene Chr14:113574905-113614623 (+)
WSB/EiJ MGP_WSBEiJ_G0020974
 protein coding gene Chr14:118059498-118096433 (+)



Homology
more
  • Human Ortholog
    IPO5, importin 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IPO5, importin 5
  • Synonyms
    IMB3, imp5, KPNB3, Pse1, RANBP5
  • Links
    NCBI Gene ID: 3843
    neXtProt AC: NX_O00410
    UniProt: O00410

  • Chr Location
    13q32.2; chr13:97953658-98024296 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    31
  • GO References
    10
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    749
  • Tissues
    22
  • cDNA Data
    515
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030662 Ensembl Gene Model | MGI Sequence Detail 36776 C57BL/6J ±  kb
transcript ENSMUST00000032898 Ensembl | MGI Sequence Detail 4518 Not Applicable  
polypeptide ENSMUSP00000032898 Ensembl | MGI Sequence Detail 1097 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 517
    cDNA 516
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1923559, MGI:2145553, MGI:2148047
References
more
  • Summaries
    All 53
    Developmental Gene Expression 3
    Gene Ontology 10
    Phenotypes 12
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory