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Kbtbd12 Gene Detail
Summary
  • Symbol
    Kbtbd12
  • Name
    kelch repeat and BTB (POZ) domain containing 12
  • Synonyms
    4833415F11Rik, 4933428M03Rik, Klhdc6
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918481
    NCBI Gene: 74589
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:88521931-88604636 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 39.51 cM, cytoband D2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2196 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918481
 protein coding gene Chr6:88521931-88614932 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031012
 protein coding gene Chr6:89947974-90038593 (-)
A/J MGP_AJ_G0030978
 protein coding gene Chr6:86490150-86578171 (-)
AKR/J MGP_AKRJ_G0030909
 protein coding gene Chr6:88977444-89061042 (-)
BALB/cJ MGP_BALBcJ_G0030991
 protein coding gene Chr6:86486950-86571624 (-)
C3H/HeJ MGP_C3HHeJ_G0030719
 protein coding gene Chr6:95390090-95479266 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031448
 protein coding gene Chr6:92379012-92467888 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028630
 protein coding gene Chr6:84644720-84731833 (-)
CAST/EiJ MGP_CASTEiJ_G0030100
 protein coding gene Chr6:89070007-89166447 (-)
CBA/J MGP_CBAJ_G0030675
 protein coding gene Chr6:95921441-96009445 (-)
DBA/2J MGP_DBA2J_G0030831
 protein coding gene Chr6:85773454-85860611 (-)
FVB/NJ MGP_FVBNJ_G0030784
 protein coding gene Chr6:84965972-85052138 (-)
LP/J MGP_LPJ_G0030908
 protein coding gene Chr6:89983413-90070975 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030817
 protein coding gene Chr6:100024111-100113637 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031475
 protein coding gene Chr6:88835279-88920766 (-)
PWK/PhJ MGP_PWKPhJ_G0029815
 protein coding gene Chr6:84754912-84841953 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029643
 protein coding gene Chr6:87647332-87731720 (-)
WSB/EiJ MGP_WSBEiJ_G0030181
 protein coding gene Chr6:89285049-89375013 (-)



Homology
more
  • Human Ortholog
    KBTBD12, kelch repeat and BTB domain containing 12
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    KBTBD12, kelch repeat and BTB domain containing 12
  • Synonyms
    KLHDC6
  • Links
    NCBI Gene ID: 166348
    neXtProt AC: NX_Q3ZCT8
    UniProt: Q3ZCT8

  • Chr Location
    3q21.3; chr3:127915232-127987677 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    3
  • cDNA Data
    8
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74589 NCBI Gene Model | MGI Sequence Detail 82706 C57BL/6J ±  kb
    transcript NM_001278671 RefSeq | MGI Sequence Detail 4628 C57BL/6  
    polypeptide Q9D618 UniProt | EBI | MGI Sequence Detail 625 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 8
      Primer pair 1
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1921839
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 1
      Gene Ontology 1
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory