About   Help   FAQ
Susd2 Gene Detail
Summary
  • Symbol
    Susd2
  • Name
    sushi domain containing 2
  • Synonyms
    1200011D11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918983
    NCBI Gene: 71733
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:75472540-75479842 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 38.56 cM, cytoband B5.3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    229 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918983
 protein coding gene Chr10:75472453-75479842 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017360
 protein coding gene Chr10:75816756-75824146 (-)
A/J MGP_AJ_G0017337
 protein coding gene Chr10:73214804-73222193 (-)
AKR/J MGP_AKRJ_G0017298
 protein coding gene Chr10:75177381-75184770 (-)
BALB/cJ MGP_BALBcJ_G0017297
 protein coding gene Chr10:73410518-73417907 (-)
C3H/HeJ MGP_C3HHeJ_G0017121
 protein coding gene Chr10:75215464-75223229 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017755
 protein coding gene Chr10:78505040-78512429 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015445
 protein coding gene Chr10:69673183-69680589 (-)
CAST/EiJ MGP_CASTEiJ_G0016692
 protein coding gene Chr10:75537276-75544661 (-)
CBA/J MGP_CBAJ_G0017093
 protein coding gene Chr10:81572744-81580133 (-)
DBA/2J MGP_DBA2J_G0017198
 protein coding gene Chr10:72517695-72525085 (-)
FVB/NJ MGP_FVBNJ_G0017191
 protein coding gene Chr10:71658719-71668674 (-)
LP/J MGP_LPJ_G0017271
 protein coding gene Chr10:76317594-76324983 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017219
 protein coding gene Chr10:83669500-83676889 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017794
 protein coding gene Chr10:75206084-75213473 (-)
PWK/PhJ MGP_PWKPhJ_G0016475
 protein coding gene Chr10:72342937-72350311 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016258
 protein coding gene Chr10:74452630-74460010 (-)
WSB/EiJ MGP_WSBEiJ_G0016755
 protein coding gene Chr10:75181187-75188603 (-)



Homology
more
  • Human Ortholog
    SUSD2, sushi domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SUSD2, sushi domain containing 2
  • Synonyms
    BK65A6.2, W5C5
  • Links
    NCBI Gene ID: 56241
    neXtProt AC: NX_Q9UGT4
    UniProt: Q9UGT4

  • Chr Location
    22q11.23; chr22:24181487-24189106 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    842
  • Tissues
    84
  • cDNA Data
    54
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000006342 Ensembl Gene Model | MGI Sequence Detail 7303 C57BL/6J ±  kb
transcript ENSMUST00000095541 Ensembl | MGI Sequence Detail 3151 Not Applicable  
polypeptide ENSMUSP00000093197 Ensembl | MGI Sequence Detail 820 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 54
    cDNA 54

    Microarray probesets 3
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:333048 Zhao B, et al., SUSD2 suppresses CD8(+) T cell antitumor immunity by targeting IL-2 receptor signaling. Nat Immunol. 2022 Nov;23(11):1588-1599
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory