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Ugt2b1 Gene Detail
Summary
  • Symbol
    Ugt2b1
  • Name
    UDP glucuronosyltransferase 2 family, polypeptide B1
  • Synonyms
    1300012D20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919023
    NCBI Gene: 71773
  • Member of
    Ugt2 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:87064498-87074362 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.56 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    247 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919023
 protein coding gene Chr5:87064497-87074389 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029676
 protein coding gene Chr5:87765975-87779337 (-)
A/J MGP_AJ_G0029644
 protein coding gene Chr5:84184843-84196844 (-)
AKR/J MGP_AKRJ_G0029592
 protein coding gene Chr5:86973619-86983424 (-)
BALB/cJ MGP_BALBcJ_G0029653
 protein coding gene Chr5:85094927-85104854 (-)
C3H/HeJ MGP_C3HHeJ_G0029376
 protein coding gene Chr5:87442509-87452397 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030107
 protein coding gene Chr5:91392440-91402169 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027349
 protein coding gene Chr5:79983106-79991675 (-)
CAST/EiJ MGP_CASTEiJ_G0028784
 protein coding gene Chr5:86788605-86800148 (-)
CBA/J MGP_CBAJ_G0029345
 protein coding gene Chr5:94318271-94330019 (-)
DBA/2J MGP_DBA2J_G0029490
 protein coding gene Chr5:84374279-84384828 (-)
FVB/NJ MGP_FVBNJ_G0029451
 protein coding gene Chr5:83294308-83304284 (-)
LP/J MGP_LPJ_G0029577
 protein coding gene Chr5:88197823-88207942 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029479
 protein coding gene Chr5:99204536-99218589 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030140
 protein coding gene Chr5:86538854-86548693 (-)
PWK/PhJ MGP_PWKPhJ_G0028508
 protein coding gene Chr5:83372127-83382588 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028341
 protein coding gene Chr5:85956223-85967187 (-)
WSB/EiJ MGP_WSBEiJ_G0028865
 protein coding gene Chr5:86919936-86930399 (-)



Homology
more
  • Human Ortholog
    UGT2B10, UDP glucuronosyltransferase family 2 member B10
  • Vertebrate Orthologs
    10
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UGT2B10, UDP glucuronosyltransferase family 2 member B10
  • Synonyms
    UDPGT2B10
  • Links
    NCBI Gene ID: 7365
    neXtProt AC: NX_P36537
    UniProt: P36537

  • Chr Location
    4q13.2; chr4:68815994-68832023 (+)  GRCh38
  • Human Ortholog
    UGT2B11, UDP glucuronosyltransferase family 2 member B11
  • Links
    NCBI Gene ID: 10720
    neXtProt AC: NX_O75310
    UniProt: O75310

  • Chr Location
    4q13.2; chr4:69199951-69224984 (-)  GRCh38
  • Human Ortholog
    UGT2B15, UDP glucuronosyltransferase family 2 member B15
  • Synonyms
    HLUG4, UDPGT2B15, UDPGT 2B8, UDPGTH3, UGT2B8
  • Links
    NCBI Gene ID: 7366
    neXtProt AC: NX_P54855
    UniProt: P54855

  • Chr Location
    4q13.2; chr4:68646597-68670652 (-)  GRCh38
  • Human Ortholog
    UGT2B17, UDP glucuronosyltransferase family 2 member B17
  • Synonyms
    BMND12, UDPGT2B17
  • Links
    NCBI Gene ID: 7367
    neXtProt AC: NX_O75795
    UniProt: O75795

  • Chr Location
    4q13.2; chr4:68537173-68576413 (-)  GRCh38
  • Human Ortholog
    UGT2B28, UDP glucuronosyltransferase family 2 member B28
  • Links
    NCBI Gene ID: 54490
    neXtProt AC: NX_Q9BY64
    UniProt: Q9BY64

  • Chr Location
    4q13.2; chr4:69280475-69295050 (+)  GRCh38
  • Human Ortholog
    UGT2B4, UDP glucuronosyltransferase family 2 member B4
  • Synonyms
    HLUG25, UDPGT2B4, UDPGTh-1, UDPGTH1, UGT2B11
  • Links
    NCBI Gene ID: 7363
    neXtProt AC: NX_P06133
    UniProt: P06133

  • Chr Location
    4q13.3; chr4:69480165-69526014 (-)  GRCh38
  • Human Ortholog
    UGT2B7, UDP glucuronosyltransferase family 2 member B7
  • Synonyms
    UDPGT 2B7, UDPGT2B7, UDPGT 2B9, UDPGTh-2, UDPGTH2, UGT2B9
  • Links
    NCBI Gene ID: 7364
    neXtProt AC: NX_P16662
    UniProt: P16662

  • Chr Location
    4q13.2; chr4:69051363-69112987 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    94
  • cDNA Data
    20
  • Literature Summary
    1
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 71773 NCBI Gene Model | MGI Sequence Detail 9865 C57BL/6J ±  kb
transcript NM_152811 RefSeq | MGI Sequence Detail 2560 FVB/N  
polypeptide NP_690024 RefSeq | MGI Sequence Detail 529 FVB/N  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • EC
    2.4.1.17
  • InterPro Domains
    IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase
    IPR050271 UDP-glycosyltransferase
    IPR035595 UDP-glycosyltransferase family, conserved site
Molecular
Reagents
less
  • All nucleic 20
    cDNA 20

    Microarray probesets 3
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 12
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory