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Mtfr2 Gene Detail
Summary
  • Symbol
    Mtfr2
  • Name
    mitochondrial fission regulator 2
  • Synonyms
    2610016C23Rik, 4933412C16Rik, Fam54a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919054
    NCBI Gene: 71804
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:20223516-20237050 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 9.75 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    340 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919054
 protein coding gene Chr10:20223491-20237415 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017055
 protein coding gene Chr10:18091616-18106438 (+)
A/J MGP_AJ_G0017033
 protein coding gene Chr10:17402871-17417291 (+)
AKR/J MGP_AKRJ_G0016997
 protein coding gene Chr10:17719758-17733435 (+)
BALB/cJ MGP_BALBcJ_G0016991
 protein coding gene Chr10:17471570-17485013 (+)
C3H/HeJ MGP_C3HHeJ_G0016816
 protein coding gene Chr10:18031987-18047034 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017453
 protein coding gene Chr10:18546246-18561463 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015158
 protein coding gene Chr10:16399736-16414476 (+)
CAST/EiJ MGP_CASTEiJ_G0016398
 protein coding gene Chr10:17904285-17921779 (+)
CBA/J MGP_CBAJ_G0016788
 protein coding gene Chr10:19379883-19396132 (+)
DBA/2J MGP_DBA2J_G0016896
 protein coding gene Chr10:17288094-17302665 (+)
FVB/NJ MGP_FVBNJ_G0016891
 protein coding gene Chr10:17042642-17056362 (+)
LP/J MGP_LPJ_G0016971
 protein coding gene Chr10:17894712-17910850 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016921
 protein coding gene Chr10:19626624-19643155 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017491
 protein coding gene Chr10:17699112-17714900 (+)
PWK/PhJ MGP_PWKPhJ_G0016183
 protein coding gene Chr10:17164570-17178178 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015966
 protein coding gene Chr10:17848300-17861076 (+)
WSB/EiJ MGP_WSBEiJ_G0016460
 protein coding gene Chr10:17782809-17798046 (+)



Homology
more
  • Human Ortholog
    MTFR2, mitochondrial fission regulator 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MTFR2, mitochondrial fission regulator 2
  • Synonyms
    DUFD1, FAM54A
  • Links
    NCBI Gene ID: 113115
    neXtProt AC: NX_Q6P444
    UniProt: Q6P444

  • Chr Location
    6q23.3; chr6:136231024-136250335 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    3
  • Gene trapped
    4
  • Targeted
    3
  • Genomic Mutations
    1 involving Mtfr2
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    29 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    735
  • Tissues
    14
  • cDNA Data
    17
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019992 Ensembl Gene Model | MGI Sequence Detail 13535 C57BL/6J ±  kb
transcript ENSMUST00000169712 Ensembl | MGI Sequence Detail 1991 Not Applicable  
polypeptide ENSMUSP00000129315 Ensembl | MGI Sequence Detail 361 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1918369
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory