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Tekt4 Gene Detail
Summary
  • Symbol
    Tekt4
  • Name
    tektin 4
  • Synonyms
    1700010L19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919090
    NCBI Gene: 71840
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:25673515-25695576 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 12.60 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    553 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919090
 protein coding gene Chr17:25673511-25695576 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023356
 protein coding gene Chr17:24545396-24550398 (+)
A/J MGP_AJ_G0023315
 protein coding gene Chr17:23843820-23848822 (+)
AKR/J MGP_AKRJ_G0023281
 protein coding gene Chr17:23945036-23950040 (+)
BALB/cJ MGP_BALBcJ_G0023320
 protein coding gene Chr17:24058950-24063952 (+)
C3H/HeJ MGP_C3HHeJ_G0023080
 protein coding gene Chr17:24323469-24328471 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023762
 protein coding gene Chr17:25604103-25609107 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021238
 protein coding gene Chr17:21304446-21309440 (+)
CAST/EiJ MGP_CASTEiJ_G0022582
 protein coding gene Chr17:24193225-24198231 (+)
CBA/J MGP_CBAJ_G0023055
 protein coding gene Chr17:26491019-26496021 (+)
DBA/2J MGP_DBA2J_G0023185
 protein coding gene Chr17:23441333-23446335 (+)
FVB/NJ MGP_FVBNJ_G0023155
 protein coding gene Chr17:23159733-23164735 (+)
LP/J MGP_LPJ_G0023262
 protein coding gene Chr17:24841357-24846359 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023174
 protein coding gene Chr17:26128255-26133257 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023802
 protein coding gene Chr17:24239634-24244636 (+)
PWK/PhJ MGP_PWKPhJ_G0022331
 protein coding gene Chr17:22195969-22200971 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022149
 protein coding gene Chr17:22323261-22328205 (+)
WSB/EiJ MGP_WSBEiJ_G0022645
 protein coding gene Chr17:24306365-24311367 (+)



Homology
more
  • Human Ortholog
    TEKT4, tektin 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TEKT4, tektin 4
  • Links
    NCBI Gene ID: 150483
    neXtProt AC: NX_Q8WW24
    UniProt: Q8WW24

  • Chr Location
    2q11.1; chr2:94871430-94876823 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotypes from 1 allele in 2 genetic backgrounds
    2 phenotypes from multigenic genotypes
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele exhibit decreased male fertility due to abnormal flagellum function.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    10
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    733
  • Tissues
    3
  • cDNA Data
    12
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000024175 Ensembl Gene Model | MGI Sequence Detail 22062 C57BL/6J ±  kb
    transcript ENSMUST00000025002 Ensembl | MGI Sequence Detail 1562 Not Applicable  
    polypeptide ENSMUSP00000025002 Ensembl | MGI Sequence Detail 447 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 12
      cDNA 12

      Microarray probesets 3
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Gene Ontology 10
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:352387 Tai L, et al., In-cell structural insight into the stability of sperm microtubule doublet. Cell Discov. 2023 Nov 21;9(1):116
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory