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Ces2f Gene Detail
Summary
  • Symbol
    Ces2f
  • Name
    carboxylesterase 2F
  • Synonyms
    2310038E17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919153
    NCBI Gene: 71903
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:105673988-105686679 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    343 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919153
 protein coding gene Chr8:105673987-105688264 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034022
 protein coding gene Chr8:107137421-107149935 (+)
A/J MGP_AJ_G0034003
 protein coding gene Chr8:102924736-102933269 (+)
AKR/J MGP_AKRJ_G0033929
 protein coding gene Chr8:105864942-105875404 (+)
BALB/cJ MGP_BALBcJ_G0033996
 protein coding gene Chr8:103086794-103095310 (+)
C3H/HeJ MGP_C3HHeJ_G0033708
 protein coding gene Chr8:106621233-106630023 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034516
 protein coding gene Chr8:111102821-111111362 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031458
 protein coding gene Chr8:96073031-96084274 (+)
CAST/EiJ MGP_CASTEiJ_G0033035
 protein coding gene Chr8:106104325-106112870 (+)
CBA/J MGP_CBAJ_G0033682
 protein coding gene Chr8:114695538-114704054 (+)
DBA/2J MGP_DBA2J_G0033836
 protein coding gene Chr8:102227773-102236138 (+)
FVB/NJ MGP_FVBNJ_G0033783
 protein coding gene Chr8:101157225-101165760 (+)
LP/J MGP_LPJ_G0033927
 protein coding gene Chr8:107359810-107370903 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033825
 protein coding gene Chr8:117927534-117936057 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034534
 protein coding gene Chr8:105814540-105823899 (+)
PWK/PhJ MGP_PWKPhJ_G0032736
 protein coding gene Chr8:101631827-101640906 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032576
 protein coding gene Chr8:104543717-104552197 (+)
WSB/EiJ MGP_WSBEiJ_G0033150
 protein coding gene Chr8:106505090-106514793 (+)



Homology
more
  • Human Ortholog
    CES2, carboxylesterase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CES2, carboxylesterase 2
  • Synonyms
    CE-2, CES2A1, iCE, PCE-2
  • Links
    NCBI Gene ID: 8824
    neXtProt AC: NX_O00748
    UniProt: O00748

  • Chr Location
    16q22.1; chr16:66934444-66945096 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced mutation exhibit epidermal and follicular hyperkeratosis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    10
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000062826 Ensembl Gene Model | MGI Sequence Detail 12692 C57BL/6J ±  kb
    transcript ENSMUST00000212820 Ensembl | MGI Sequence Detail 4925 Not Applicable  
    polypeptide ENSMUSP00000148278 Ensembl | MGI Sequence Detail 561 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 10
      cDNA 10

      Microarray probesets 3
    References
    more
    • Summaries
      All 26
      Gene Ontology 3
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory