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Naa50 Gene Detail
Summary
  • Symbol
    Naa50
  • Name
    N(alpha)-acetyltransferase 50, NatE catalytic subunit
  • Synonyms
    2600005K24Rik, 2810441M03Rik, Mak3p, Nat13, Nat5, San
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919367
    NCBI Gene: 72117
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:43960193-43983729 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 28.47 cM, cytoband B4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    380 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919367
 protein coding gene Chr16:43960154-43983825 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022835
 protein coding gene Chr16:42870392-42898720 (+)
A/J MGP_AJ_G0022800
 protein coding gene Chr16:40940087-40963840 (+)
AKR/J MGP_AKRJ_G0022772
 protein coding gene Chr16:42252204-42275854 (+)
BALB/cJ MGP_BALBcJ_G0022801
 protein coding gene Chr16:40928426-40951404 (+)
C3H/HeJ MGP_C3HHeJ_G0022565
 protein coding gene Chr16:42447358-42472983 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023248
 protein coding gene Chr16:43861025-43882921 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020763
 protein coding gene Chr16:40994412-41016359 (+)
CAST/EiJ MGP_CASTEiJ_G0022091
 protein coding gene Chr16:42646434-42671204 (+)
CBA/J MGP_CBAJ_G0022536
 protein coding gene Chr16:45707481-45735322 (+)
DBA/2J MGP_DBA2J_G0022668
 protein coding gene Chr16:40684250-40707537 (+)
FVB/NJ MGP_FVBNJ_G0022643
 protein coding gene Chr16:40643436-40665501 (+)
LP/J MGP_LPJ_G0022736
 protein coding gene Chr16:42584354-42610968 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022662
 protein coding gene Chr16:45101854-45138317 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023263
 protein coding gene Chr16:42279164-42303111 (+)
PWK/PhJ MGP_PWKPhJ_G0021831
 protein coding gene Chr16:41068486-41092562 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021662
 protein coding gene Chr16:42174815-42200894 (+)
WSB/EiJ MGP_WSBEiJ_G0022135
 protein coding gene Chr16:42372838-42395985 (+)



Homology
more
  • Human Ortholog
    NAA50, N-alpha-acetyltransferase 50, NatE catalytic subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NAA50, N-alpha-acetyltransferase 50, NatE catalytic subunit
  • Synonyms
    hNaa50p, MAK3, NAT13, NAT13P, NAT5, NAT5P, SAN
  • Links
    NCBI Gene ID: 80218
    neXtProt AC: NX_Q9GZZ1
    UniProt: Q9GZZ1

  • Chr Location
    3q13.31; chr3:113716458-113746300 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    27
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    803
  • Tissues
    97
  • cDNA Data
    212
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000022698 Ensembl Gene Model | MGI Sequence Detail 23537 C57BL/6J ±  kb
    transcript ENSMUST00000159514 Ensembl | MGI Sequence Detail 3756 Not Applicable  
    polypeptide ENSMUSP00000125517 Ensembl | MGI Sequence Detail 175 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 213
      cDNA 212
      Primer pair 1

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1919982, MGI:2146622
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 2
      Gene Ontology 8
      Phenotypes 13
    • Earliest
      J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory