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2510002D24Rik Gene Detail
Summary
  • Symbol
    2510002D24Rik
  • Name
    RIKEN cDNA 2510002D24 gene
  • Synonyms
    2410043I01Rik, Pants
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919557
    NCBI Gene: 72307
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:18655328-18658910 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 11.67 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    12 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919557
 protein coding gene Chr16:18655263-18658910 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022620
 protein coding gene Chr16:16101893-16105481 (+)
A/J MGP_AJ_G0022581
 protein coding gene Chr16:15293533-15297000 (+)
AKR/J MGP_AKRJ_G0022558
 protein coding gene Chr16:15911260-15917549 (+)
BALB/cJ MGP_BALBcJ_G0022586
 protein coding gene Chr16:15445095-15448700 (+)
C3H/HeJ MGP_C3HHeJ_G0022353
 protein coding gene Chr16:16063182-16066771 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023035
 protein coding gene Chr16:16418394-16422003 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020555
 protein coding gene Chr16:15327668-15330903 (+)
CAST/EiJ MGP_CASTEiJ_G0021880
 protein coding gene Chr16:15961113-15964501 (+)
CBA/J MGP_CBAJ_G0022322
 protein coding gene Chr16:17087460-17095093 (+)
DBA/2J MGP_DBA2J_G0022454
 protein coding gene Chr16:15205252-15208823 (+)
FVB/NJ MGP_FVBNJ_G0022429
 protein coding gene Chr16:15269421-15273005 (+)
LP/J MGP_LPJ_G0022521
 protein coding gene Chr16:15848989-15859017 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022451
 protein coding gene Chr16:16726928-16735278 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023046
 protein coding gene Chr16:15829940-15833408 (+)
PWK/PhJ MGP_PWKPhJ_G0021622
 protein coding gene Chr16:15500425-15503923 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021450
 protein coding gene Chr16:15790388-15791296 (+)
WSB/EiJ MGP_WSBEiJ_G0021926
 protein coding gene Chr16:15855739-15859279 (+)



Homology
more
  • Human Ortholog
    C22orf39, chromosome 22 open reading frame 39
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C22orf39, chromosome 22 open reading frame 39
  • Synonyms
    Pants
  • Links
    NCBI Gene ID: 128977
    neXtProt AC: NX_Q6P5X5
    UniProt: Q6P5X5

  • Chr Location
    22q11.21; chr22:19351368-19447711 (-)  GRCh38
Human Diseases
less
  • References
    4 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 2 genetic backgrounds
    57 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mutant mice are viable, and have no obvious abnormalites.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    809
  • Tissues
    32
  • cDNA Data
    16
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000071632 Ensembl Gene Model | MGI Sequence Detail 3583 C57BL/6J ±  kb
    transcript ENSMUST00000055413 Ensembl | MGI Sequence Detail 1281 Not Applicable  
    polypeptide ENSMUSP00000060363 Ensembl | MGI Sequence Detail 105 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000059863 synaptic plasticity regulator PANTS
      (term hierarchy)
    • InterPro Domains
      IPR021475 Plasticity-Associated Neural Transcript Short/Early meiotic induction protein 1-like
    Molecular
    Reagents
    less
    • All nucleic 18
      cDNA 16
      Primer pair 2

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:1858447
    References
    more
    • Summaries
      All 78
      Developmental Gene Expression 2
      Diseases 4
      Gene Ontology 1
      Phenotypes 57
    • Earliest
      J:60871 Lund J, et al., Comparative sequence analysis of 634 kb of the mouse chromosome 16 region of conserved synteny with the human velocardiofacial syndrome region on chromosome 22q11.2. Genomics. 2000 Feb 1;63(3):374-83
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    11/19/2024
    MGI 6.24     		The Jackson Laboratory