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Pcf11 Gene Detail
Summary
  • Symbol
    Pcf11
  • Name
    PCF11 cleavage and polyadenylation factor subunit
  • Synonyms
    2500001H09Rik, 5730417B17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919579
    NCBI Gene: 74737
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:92292751-92319142 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 51.56 cM, cytoband E2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    501 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919579
 protein coding gene Chr7:92292666-92319284 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032513
 protein coding gene Chr7:95196100-95228203 (-)
A/J MGP_AJ_G0032487
 protein coding gene Chr7:92822503-92848195 (-)
AKR/J MGP_AKRJ_G0032423
 protein coding gene Chr7:95035988-95062951 (-)
BALB/cJ MGP_BALBcJ_G0032498
 protein coding gene Chr7:92499180-92524690 (-)
C3H/HeJ MGP_C3HHeJ_G0032213
 protein coding gene Chr7:95404527-95432006 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032996
 protein coding gene Chr7:98876004-98905629 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029991
 protein coding gene Chr7:95614178-95639741 (-)
CAST/EiJ MGP_CASTEiJ_G0031540
 protein coding gene Chr7:86890096-86923233 (-)
CBA/J MGP_CBAJ_G0032180
 protein coding gene Chr7:102207519-102237238 (-)
DBA/2J MGP_DBA2J_G0032332
 protein coding gene Chr7:91256047-91282015 (-)
FVB/NJ MGP_FVBNJ_G0032288
 protein coding gene Chr7:91088131-91114333 (-)
LP/J MGP_LPJ_G0032421
 protein coding gene Chr7:96444223-96471624 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032322
 protein coding gene Chr7:103333389-103373941 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033018
 protein coding gene Chr7:94346976-94372492 (-)
PWK/PhJ MGP_PWKPhJ_G0031258
 protein coding gene Chr7:84325489-84353865 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031101
 protein coding gene Chr7:81656287-81682373 (-)
WSB/EiJ MGP_WSBEiJ_G0031657
 protein coding gene Chr7:95001962-95034616 (-)



Homology
more
  • Human Ortholog
    PCF11, PCF11 cleavage and polyadenylation factor subunit
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PCF11, PCF11 cleavage and polyadenylation factor subunit
  • Links
    NCBI Gene ID: 51585
    neXtProt AC: NX_O94913
    UniProt: O94913

  • Chr Location
    11q14.1; chr11:83156988-83187451 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    17
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041328 Ensembl Gene Model | MGI Sequence Detail 26392 C57BL/6J ±  kb
transcript ENSMUST00000119954 Ensembl | MGI Sequence Detail 5995 Not Applicable  
polypeptide ENSMUSP00000113717 Ensembl | MGI Sequence Detail 1553 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 17

    Microarray probesets 6
Other
Accession IDs
less
MGI:1921987, MGI:2142322
References
more
  • Summaries
    All 51
    Gene Ontology 5
    Phenotypes 27
  • Earliest
    J:141526 Russell LB, et al., Analysis of the albino-locus region of the mouse. III. Time of death of prenatal lethals. Genetics. 1979 May;92(1):205-13
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory