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Trmt11 Gene Detail
Summary
  • Symbol
    Trmt11
  • Name
    tRNA methyltransferase 11
  • Synonyms
    2410075D05Rik, 3110045I18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920931
    NCBI Gene: 73681
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:30410221-30476745 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 17.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1843 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1920931
 protein coding gene Chr10:30410218-30477598 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017116
 protein coding gene Chr10:28748629-28809328 (-)
A/J MGP_AJ_G0017093
 protein coding gene Chr10:27900738-27966884 (-)
AKR/J MGP_AKRJ_G0017053
 protein coding gene Chr10:28334351-28403204 (-)
BALB/cJ MGP_BALBcJ_G0017056
 protein coding gene Chr10:27975323-28046146 (-)
C3H/HeJ MGP_C3HHeJ_G0016876
 protein coding gene Chr10:28605107-28672927 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017514
 protein coding gene Chr10:29597499-29665510 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015212
 protein coding gene Chr10:26350171-26410684 (-)
CAST/EiJ MGP_CASTEiJ_G0016455
 protein coding gene Chr10:28668507-28733115 (-)
CBA/J MGP_CBAJ_G0016850
 protein coding gene Chr10:31011718-31081690 (-)
DBA/2J MGP_DBA2J_G0016955
 protein coding gene Chr10:27579121-27639577 (-)
FVB/NJ MGP_FVBNJ_G0016950
 protein coding gene Chr10:27188986-27255626 (-)
LP/J MGP_LPJ_G0017032
 protein coding gene Chr10:28741773-28819926 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016980
 protein coding gene Chr10:31188466-31281691 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017550
 protein coding gene Chr10:28245072-28314712 (-)
PWK/PhJ MGP_PWKPhJ_G0016237
 protein coding gene Chr10:27345404-27405901 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016021
 protein coding gene Chr10:28117946-28260978 (-)
WSB/EiJ MGP_WSBEiJ_G0016518
 protein coding gene Chr10:28384791-28454964 (-)



Homology
more
  • Human Ortholog
    TRMT11, tRNA methyltransferase 11 homolog
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRMT11, tRNA methyltransferase 11 homolog
  • Synonyms
    C6orf75, MDS024, TRM11, TRMT11-1
  • Links
    NCBI Gene ID: 60487
    neXtProt AC: NX_Q7Z4G4
    UniProt: Q7Z4G4

  • Chr Location
    6q22.32; chr6:125986479-126272343 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    1
  • cDNA Data
    27
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000019792 Ensembl Gene Model | MGI Sequence Detail 66525 C57BL/6J ±  kb
transcript ENSMUST00000019927 Ensembl | MGI Sequence Detail 2359 Not Applicable  
polypeptide ENSMUSP00000019927 Ensembl | MGI Sequence Detail 460 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000016678 tRNA guanosine-2'-O-methyltransferase TRM11
    (term hierarchy)
  • EC
    2.1.1.-
  • InterPro Domains
    IPR002052 DNA methylase, N-6 adenine-specific, conserved site
    IPR000241 Ribosomal RNA large subunit methyltransferase K/L-like, methyltransferase domain
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
    IPR016691 tRNA guanosine-2'-O-methyltransferase, TRM11
  • GlyGen
    Q9CWH5 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 27
    cDNA 27

    Microarray probesets 5
Other
Accession IDs
less
MGI:1920471, MGI:2143827
References
more
  • Summaries
    All 32
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 10
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory