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Cep350 Gene Detail
Summary
  • Symbol
    Cep350
  • Name
    centrosomal protein 350
  • Synonyms
    4933409L06Rik, 6430546F08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921331
    NCBI Gene: 74081
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:155720710-155848976 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 67.64 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2869 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921331
 protein coding gene Chr1:155720710-155849001 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016617
 protein coding gene Chr1:160786868-160927503 (-)
A/J MGP_AJ_G0016598
 protein coding gene Chr1:154343172-154468934 (-)
AKR/J MGP_AKRJ_G0016564
 protein coding gene Chr1:159071659-159200590 (-)
BALB/cJ MGP_BALBcJ_G0016559
 protein coding gene Chr1:154845674-154972881 (-)
C3H/HeJ MGP_C3HHeJ_G0016383
 protein coding gene Chr1:159197195-159323500 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017020
 protein coding gene Chr1:166303235-166441746 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014729
 protein coding gene Chr1:146558719-146690470 (-)
CAST/EiJ MGP_CASTEiJ_G0015963
 protein coding gene Chr1:158730413-158862986 (-)
CBA/J MGP_CBAJ_G0016358
 protein coding gene Chr1:172157544-172294602 (-)
DBA/2J MGP_DBA2J_G0016464
 protein coding gene Chr1:153309428-153435970 (-)
FVB/NJ MGP_FVBNJ_G0016462
 protein coding gene Chr1:151770088-151895994 (-)
LP/J MGP_LPJ_G0016535
 protein coding gene Chr1:161936380-162067272 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016487
 protein coding gene Chr1:179753200-179883847 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017056
 protein coding gene Chr1:158874991-159003096 (-)
PWK/PhJ MGP_PWKPhJ_G0015749
 protein coding gene Chr1:152377457-152504715 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015536
 protein coding gene Chr1:157615262-157750556 (-)
WSB/EiJ MGP_WSBEiJ_G0016025
 protein coding gene Chr1:158961827-159098869 (-)



Homology
more
  • Human Ortholog
    CEP350, centrosomal protein 350
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CEP350, centrosomal protein 350
  • Synonyms
    CAP350, GM133
  • Links
    NCBI Gene ID: 9857
    neXtProt AC: NX_Q5VT06
    UniProt: Q5VT06

  • Chr Location
    1q25.2; chr1:179954674-180114880 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    5
  • cDNA Data
    103
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74081 NCBI Gene Model | MGI Sequence Detail 128267 C57BL/6J ±  kb
transcript NM_001039184 RefSeq | MGI Sequence Detail 13238 C57BL/6  
polypeptide E9Q309 UniProt | EBI | MGI Sequence Detail 3095 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000005350 centrosome-associated protein 350
    (term hierarchy)
  • InterPro Domains
    IPR000938 CAP Gly-rich domain
    IPR036859 CAP Gly-rich domain superfamily
    IPR028750 Centrosome-associated protein 350/Coiled-coil domain-containing protein 187
    IPR025486 Domain of unknown function DUF4378
  • GlyGen
    E9Q309 3 sites, 1 O-linked glycan (3 sites)
Molecular
Reagents
less
  • All nucleic 104
    cDNA 103
    Primer pair 1

    Microarray probesets 6
Other
Accession IDs
less
MGI:2442897
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory