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Acoxl Gene Detail
Summary
  • Symbol
    Acoxl
  • Name
    acyl-Coenzyme A oxidase-like
  • Synonyms
    1200014P05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921371
    NCBI Gene: 74121
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:127680796-127965793 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 62.10 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    6506 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921371
 protein coding gene Chr2:127680717-127968172 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026470
 protein coding gene Chr2:131127670-131441410 (+)
A/J MGP_AJ_G0026434
 protein coding gene Chr2:125822151-126123210 (+)
AKR/J MGP_AKRJ_G0026409
 protein coding gene Chr2:129422977-129715047 (+)
BALB/cJ MGP_BALBcJ_G0026446
 protein coding gene Chr2:126088747-126381298 (+)
C3H/HeJ MGP_C3HHeJ_G0026189
 protein coding gene Chr2:129919590-130225622 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026891
 protein coding gene Chr2:135251009-135556968 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024268
 protein coding gene Chr2:120658473-120952017 (+)
CAST/EiJ MGP_CASTEiJ_G0025650
 protein coding gene Chr2:130130675-130438598 (+)
CBA/J MGP_CBAJ_G0026169
 protein coding gene Chr2:140260546-140579818 (+)
DBA/2J MGP_DBA2J_G0026303
 protein coding gene Chr2:125221542-125519500 (+)
FVB/NJ MGP_FVBNJ_G0026267
 protein coding gene Chr2:123880207-124164524 (+)
LP/J MGP_LPJ_G0026408
 protein coding gene Chr2:131377237-131680058 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026287
 protein coding gene Chr2:144262223-144564072 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026946
 protein coding gene Chr2:129433128-129733731 (+)
PWK/PhJ MGP_PWKPhJ_G0025386
 protein coding gene Chr2:124788967-125082367 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025188
 protein coding gene Chr2:128529460-128835232 (+)
WSB/EiJ MGP_WSBEiJ_G0025724
 protein coding gene Chr2:130341277-130644383 (+)



Homology
more
  • Human Ortholog
    ACOXL, acyl-CoA oxidase like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ACOXL, acyl-CoA oxidase like
  • Synonyms
    ACOX4
  • Links
    NCBI Gene ID: 55289
    neXtProt AC: NX_Q9NUZ1
    UniProt: Q9NUZ1

  • Chr Location
    2q13; chr2:110732539-111118548 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000027380 Ensembl Gene Model | MGI Sequence Detail 284998 C57BL/6J ±  kb
    transcript ENSMUST00000028859 Ensembl | MGI Sequence Detail 2842 Not Applicable  
    polypeptide ENSMUSP00000028859 Ensembl | MGI Sequence Detail 632 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000003645 acyl-coenzyme A oxidase-like protein
      (term hierarchy)
    • EC
      1.3.3.-
    • InterPro Domains
      IPR036250 Acyl-CoA dehydrogenase-like, C-terminal
      IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily
      IPR012258 Acyl-CoA oxidase
      IPR002655 Acyl-CoA oxidase, C-terminal
      IPR006091 Acyl-CoA oxidase/dehydrogenase, middle domain
      IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2139241
    References
    more
    • Summaries
      All 30
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory