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Lrrc2 Gene Detail
Summary
  • Symbol
    Lrrc2
  • Name
    leucine rich repeat containing 2
  • Synonyms
    2400002D05Rik, 4933431K03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921499
    NCBI Gene: 74249
  • Alliance
    gene page
  • Transcription Start Sites
    14 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:110780613-110813134 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 60.79 cM, cytoband F2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1178 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921499
 protein coding gene Chr9:110780613-110813134 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035366
 protein coding gene Chr9:113150971-113177042 (+)
A/J MGP_AJ_G0035347
 protein coding gene Chr9:109019807-109048217 (+)
AKR/J MGP_AKRJ_G0035278
 protein coding gene Chr9:111731078-111754701 (+)
BALB/cJ MGP_BALBcJ_G0035342
 protein coding gene Chr9:108779217-108801223 (+)
C3H/HeJ MGP_C3HHeJ_G0035050
 protein coding gene Chr9:112238265-112267370 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035864
 protein coding gene Chr9:116268061-116299177 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032750
 protein coding gene Chr9:106234714-106262380 (+)
CAST/EiJ MGP_CASTEiJ_G0034356
 protein coding gene Chr9:112039946-112065873 (+)
CBA/J MGP_CBAJ_G0035017
 protein coding gene Chr9:120551201-120577815 (+)
DBA/2J MGP_DBA2J_G0035176
 protein coding gene Chr9:108479982-108503154 (+)
FVB/NJ MGP_FVBNJ_G0035123
 protein coding gene Chr9:107321380-107346033 (+)
LP/J MGP_LPJ_G0035255
 protein coding gene Chr9:113440198-113465630 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035163
 protein coding gene Chr9:121865771-121891843 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035884
 protein coding gene Chr9:112082266-112111106 (+)
PWK/PhJ MGP_PWKPhJ_G0034063
 protein coding gene Chr9:108724671-108751682 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033898
 protein coding gene Chr9:112161355-112195686 (+)
WSB/EiJ MGP_WSBEiJ_G0034477
 protein coding gene Chr9:111952807-111977357 (+)



Homology
more
  • Human Ortholog
    LRRC2, leucine rich repeat containing 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC2, leucine rich repeat containing 2
  • Links
    NCBI Gene ID: 79442
    neXtProt AC: NX_Q9BYS8
    UniProt: Q9BYS8

  • Chr Location
    3p21.31; chr3:46515385-46606948 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    778
  • Tissues
    2
  • cDNA Data
    18
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 74249 NCBI Gene Model | MGI Sequence Detail 32522 C57BL/6J ±  kb
transcript NM_028838 RefSeq | MGI Sequence Detail 3657 ZRU/MplStud  
polypeptide Q8VDB8 UniProt | EBI | MGI Sequence Detail 371 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Primer pair 2

    Microarray probesets 5
Other
Accession IDs
less
MGI:1922983
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 2
    Phenotypes 14
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory