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Moxd1 Gene Detail
Summary
  • Symbol
    Moxd1
  • Name
    monooxygenase, DBH-like 1
  • Synonyms
    3230402N08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921582
    NCBI Gene: 59012
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:24099415-24178681 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 10, 11.48 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2728 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921582
 protein coding gene Chr10:24099415-24178688 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017091
 protein coding gene Chr10:22184220-22268630 (+)
A/J MGP_AJ_G0017068
 protein coding gene Chr10:21529076-21611058 (+)
AKR/J MGP_AKRJ_G0017028
 protein coding gene Chr10:21879291-21963228 (+)
BALB/cJ MGP_BALBcJ_G0017031
 protein coding gene Chr10:21614749-21694396 (+)
C3H/HeJ MGP_C3HHeJ_G0016851
 protein coding gene Chr10:22095424-22172961 (+)
C57BL/6NJ MGP_C57BL6NJ_G0017489
 protein coding gene Chr10:22875091-22957658 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0015187
 protein coding gene Chr10:20247775-20324545 (+)
CAST/EiJ MGP_CASTEiJ_G0016430
 protein coding gene Chr10:22017961-22099148 (+)
CBA/J MGP_CBAJ_G0016825
 protein coding gene Chr10:23905208-23986655 (+)
DBA/2J MGP_DBA2J_G0016930
 protein coding gene Chr10:21267412-21348508 (+)
FVB/NJ MGP_FVBNJ_G0016925
 protein coding gene Chr10:20982495-21062929 (+)
LP/J MGP_LPJ_G0017007
 protein coding gene Chr10:22184608-22263431 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016955
 protein coding gene Chr10:24015895-24103654 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0017525
 protein coding gene Chr10:21754237-21834968 (+)
PWK/PhJ MGP_PWKPhJ_G0016212
 protein coding gene Chr10:21045012-21119032 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015996
 protein coding gene Chr10:21562863-21644257 (+)
WSB/EiJ MGP_WSBEiJ_G0016493
 protein coding gene Chr10:21856973-21941094 (+)



Homology
more
  • Human Ortholog
    MOXD1, monooxygenase DBH like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MOXD1, monooxygenase DBH like 1
  • Synonyms
    dJ248E1.1, MOX, PRO5780
  • Links
    NCBI Gene ID: 26002
    neXtProt AC: NX_Q6UVY6
    UniProt: Q6UVY6

  • Chr Location
    6q23.2; chr6:132296055-132401475 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    779
  • Tissues
    49
  • cDNA Data
    43
  • Literature Summary
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 59012 NCBI Gene Model | MGI Sequence Detail 79267 C57BL/6J ±  kb
    transcript NM_021509 RefSeq | MGI Sequence Detail 3083 C57BL/6  
    polypeptide Q9CXI3 UniProt | EBI | MGI Sequence Detail 613 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000010529 DBH-like monooxygenase protein 1
      (term hierarchy)
    • EC
      1.14.17.-
    • InterPro Domains
      IPR045266 Copper-dependent monooxygenases, DOMON domain
      IPR024548 Copper type II ascorbate-dependent monooxygenase, C-terminal
      IPR014784 Copper type II, ascorbate-dependent monooxygenase-like, C-terminal
      IPR000323 Copper type II, ascorbate-dependent monooxygenase, N-terminal
      IPR036939 Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily
      IPR005018 DOMON domain
      IPR000945 Dopamine beta-hydroxylase-like
      IPR008977 PHM/PNGase F domain superfamily
      IPR028460 Tyramine beta-hydroxylase/Dopamine beta-hydroxylase
    • GlyGen
      Q9CXI3 4 sites, 2 N-linked glycans (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 45
      cDNA 43
      Primer pair 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 9
      Gene Ontology 4
      Phenotypes 12
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory